Chx10 Activators
Chx10 Activators refer to a class of chemical compounds or molecules that have the capability to stimulate or enhance the activity of the Chx10 gene within biological systems. Chx10, short for Ceh-10 homeodomain-containing homolog, is a critical transcription factor gene that plays a pivotal role in the development and differentiation of various cell types, particularly in the context of neural development. These activators are essential for the proper regulation of Chx10 gene expression, and they exert their influence through molecular mechanisms that facilitate gene transcription, leading to an increased production of Chx10 protein.
The Chx10 gene is highly conserved across species and is predominantly associated with eye and neural development. It is instrumental in guiding the fate of progenitor cells into specific lineages, such as bipolar cells in the retina and certain types of interneurons in the central nervous system. Chx10 activators are particularly significant in developmental biology and molecular genetics, as they shed light on the intricate regulatory networks involved in cell fate determination. Researchers investigate these activators to gain insights into the mechanisms governing embryonic development and tissue regeneration, unraveling the complexities of gene expression patterns and how they contribute to the formation of specialized cell types.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid influences Chx10 expression during retinal development, potentially by modulating gene transcription pathways that involve homeobox genes. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic acid, a histone deacetylase inhibitor, can affect the expression of various genes, including Chx10, by altering chromatin structure and accessibility. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
(-)-Epigallocatechin Gallate may affect Chx10 expression by influencing signaling pathways that include transcription factors or by its role as an antioxidant. | ||||||
Taurine | 107-35-7 | sc-202354 sc-202354A | 25 g 500 g | $48.00 $102.00 | 1 | |
Taurine has been shown to have various neuroprotective roles, which could include the modulation of genes like Chx10, involved in retinal development. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, which increases cAMP and can lead to the activation of genes such as Chx10 through the cAMP response element-binding protein (CREB). | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
As a cAMP analog, db-cAMP mimics the action of cAMP and can promote the expression of genes like Chx10 via CREB or other cAMP-responsive pathways. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin, through its signaling pathways, can affect gene expression and has been suggested to potentially modulate homeobox genes like Chx10. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium influences various signaling pathways, such as the Wnt signaling pathway, which can affect the expression of developmental genes like Chx10. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate, as a histone deacetylase inhibitor, can induce transcriptional changes, potentially influencing Chx10 expression. | ||||||
Kinetin | 525-79-1 | sc-207780 sc-207780A | 1 g 5 g | $38.00 $48.00 | ||
Kinetin affects cellular growth and differentiation processes, which could include the upregulation of genes essential for development such as Chx10. | ||||||