Date published: 2026-5-13

1-800-457-3801

SCBT Portrait Logo
Seach Input

CEP97 Inhibitors

CEP97 inhibitors are primarily chemicals that indirectly affect the functions of CEP97 by targeting cellular processes and signaling pathways crucial for centrosome dynamics and ciliogenesis. These inhibitors focus on disrupting or modulating the cell cycle, microtubule dynamics, and kinases that play vital roles in centrosome functions. Since CEP97 is intricately linked to the regulation of these processes, altering them can indirectly inhibit the functional aspects of CEP97 in the cell. The primary mechanism through which these inhibitors work includes the disruption of microtubule dynamics (Nocodazole, Paclitaxel, Griseofulvin, Vinblastine, Vincristine) and the inhibition of key kinases (Purvalanol A, Roscovitine, ZM447439, BI 2536) involved in cell cycle progression and centrosome maturation. Additionally, some of these chemicals target kinesin motor proteins (Monastrol, S-Trityl-L-cysteine, Kinesore), which are crucial for spindle formation and function during cell division. By targeting these pathways, the inhibitors can exert an indirect effect on CEP97, potentially influencing its role in centrosome-related functions and ciliogenesis.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Purvalanol A

212844-53-6sc-224244
sc-224244A
1 mg
5 mg
$72.00
$297.00
4
(2)

Purvalanol A is a potent cyclin-dependent kinase (CDK) inhibitor, which can disrupt cell cycle progression, indirectly affecting CEP97 functions in centrosome dynamics and ciliogenesis.

Roscovitine

186692-46-6sc-24002
sc-24002A
1 mg
5 mg
$94.00
$265.00
42
(2)

Roscovitine, another CDK inhibitor, can indirectly influence CEP97 by altering cell cycle control mechanisms that are crucial for centrosome functions.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$59.00
$85.00
$143.00
$247.00
38
(2)

Nocodazole acts by disrupting microtubule dynamics, a process essential for proper centrosome function, indirectly affecting CEP97's role in cell division.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$41.00
$74.00
$221.00
$247.00
$738.00
$1220.00
39
(2)

Paclitaxel stabilizes microtubules, which can indirectly impact CEP97 by affecting microtubule-dependent processes in the centrosome.

ZM-447439

331771-20-1sc-200696
sc-200696A
1 mg
10 mg
$153.00
$356.00
15
(1)

ZM447439 is an Aurora kinase inhibitor, potentially affecting CEP97 by disrupting kinases involved in centrosome maturation and separation.

BI 2536

755038-02-9sc-364431
sc-364431A
5 mg
50 mg
$151.00
$525.00
8
(1)

BI 2536, a Plk1 inhibitor, can indirectly inhibit CEP97 by interfering with polo-like kinase 1, which is essential for proper centrosome function.

Monastrol

254753-54-3sc-202710
sc-202710A
1 mg
5 mg
$120.00
$233.00
10
(1)

Monastrol, a kinesin Eg5 inhibitor, can alter centrosome dynamics, indirectly affecting CEP97's involvement in cell division and spindle formation.

S-Trityl-L-cysteine

2799-07-7sc-202799
sc-202799A
1 g
5 g
$32.00
$66.00
6
(1)

This chemical inhibits mitotic kinesin Eg5, which can lead to indirect inhibition of CEP97 by affecting spindle fiber dynamics and centrosome functions.

Griseofulvin

126-07-8sc-202171A
sc-202171
sc-202171B
5 mg
25 mg
100 mg
$85.00
$220.00
$598.00
4
(2)

Griseofulvin disrupts microtubule function, potentially impacting CEP97 indirectly by affecting cellular structures vital for its functions.

Vinblastine

865-21-4sc-491749
sc-491749A
sc-491749B
sc-491749C
sc-491749D
10 mg
50 mg
100 mg
500 mg
1 g
$102.00
$235.00
$459.00
$1749.00
$2958.00
4
(0)

Vinblastine inhibits microtubule assembly, potentially influencing CEP97 indirectly by disrupting essential centrosome and spindle activities.