CD55 Inhibitors
CD55, or decay-accelerating factor (DAF), is integral to the body's innate immune response, specifically within the complement system. By accelerating the decay of C3 convertases, CD55 acts as a safeguard, ensuring that the complement system, which aids in clearing pathogens, does not inadvertently damage the body's own cells. This protective mechanism is crucial in preventing self-directed complement-mediated cytotoxicity.
Inhibitors targeting CD55 have been developed to modulate its function. These inhibitors can either impede CD55's ability to interact with components of the complement system or influence its expression levels on the cell surface. The exploration and development of CD55 inhibitors are of substantial importance in immunology. By manipulating CD55's activity, researchers can delve deeper into understanding autoimmune diseases, transplant rejection, and other conditions where the complement system might be inappropriately activated. The nuanced understanding of how CD55 inhibitors function can pave the way for interventions in diseases where the regulation of the complement system is imperative.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin might down-regulate CD55 expression in certain cells, increasing complement susceptibility. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG can reduce CD55 expression in certain cancer cells, increasing their susceptibility to complement. | ||||||
Niflumic acid | 4394-00-7 | sc-204820 | 5 g | $32.00 | 3 | |
Niflumic acid may down-regulate CD55 expression, affecting cell protection against complement. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin might suppress CD55 expression in certain cancer cells, increasing complement-mediated cytotoxicity. | ||||||
Lovastatin | 75330-75-5 | sc-200850 sc-200850A sc-200850B | 5 mg 25 mg 100 mg | $29.00 $90.00 $339.00 | 12 | |
Lovastatin can reduce CD55 expression, potentially affecting protection against complement attack. | ||||||
Progesterone | 57-83-0 | sc-296138A sc-296138 sc-296138B | 1 g 5 g 50 g | $20.00 $52.00 $298.00 | 3 | |
Progesterone might down-regulate CD55 expression in certain cells, affecting complement protection. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2 might suppress CD55 expression in certain cells, affecting protection against complement. | ||||||