CD2BP2 Activators
The class of chemicals referred to as CD2BP2 activators encompasses various compounds that can modulate the expression or activity of the CD2BP2 (T-cell activation RhoGTPase-activating protein) gene or protein. These compounds are primarily involved in influencing immune responses and cellular processes. One subset of CD2BP2 activators includes phorbol 12-myristate 13-acetate (PMA) and tumor necrosis factor-alpha (TNF-alpha). PMA activates protein kinase C (PKC) and downstream signaling pathways, affecting gene expression, including CD2BP2. TNF-alpha, on the other hand, activates signaling pathways like NF-kappaB, which can indirectly impact CD2BP2 gene expression by promoting inflammation and immune responses. Another group of compounds includes lipopolysaccharide (LPS). LPS stimulates Toll-like receptors (TLRs) and downstream signaling pathways, which can influence CD2BP2 expression through NF-kappaB activation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates PKC and downstream pathways, influencing gene expression, potentially including CD2BP2. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
Stimulates TLRs and downstream signaling, potentially affecting CD2BP2 expression via NF-kappaB. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Modulates immune responses and gene expression, potentially impacting CD2BP2 expression. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Inhibits calcineurin, affecting T-cell activation, which could indirectly influence CD2BP2. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Exhibits potential immunomodulatory effects, which might indirectly affect CD2BP2 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Possesses anti-inflammatory properties, potentially influencing immune responses and CD2BP2 expression. | ||||||
Methylprednisolone | 83-43-2 | sc-205749 sc-205749A | 100 mg 500 mg | $115.00 $260.00 | 1 | |
Corticosteroid that modulates immune responses and gene expression, potentially affecting CD2BP2. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $76.00 $148.00 | 9 | |
Influence T-cell activation and cytokine production, indirectly impacting CD2BP2 in immune cells. | ||||||