CD2 Activators
CD2 activators comprise a diverse array of chemicals with distinct mechanisms of action on the intricate signaling pathways governing immune responses. Betulinic Acid indirectly activates CD2 by modulating the NF-κB signaling pathway, enhancing the transcriptional regulation of CD2. A769662, an AMP-activated protein kinase (AMPK) activator, directly influences CD2 activation by modulating AMPK-dependent pathways, impacting the intricate network of signaling pathways regulating CD2. BML-275, also known as Dorsomorphin, indirectly activates CD2 by inhibiting mTOR through AMPK activation. Curcumin modulates the NF-κB signaling pathway, providing an indirect mechanism for activating CD2-mediated immune responses by enhancing CD2 transcriptional regulation. SC79, an Akt activator, directly influences CD2 activation by modulating Akt-dependent pathways, providing insights into the specific molecular events regulated by CD2.
AICAR, another AMPK activator, directly influences CD2 activation by modulating AMPK-dependent pathways, impacting the intricate network of signaling pathways regulating CD2. GSK690693, an Akt activator, directly influences CD2 activation by modulating Akt-dependent pathways, offering insights into the specific molecular events regulated by CD2. 2-Deoxy-D-glucose (2-DG) modulates AMPK signaling, providing an indirect mechanism for activating CD2-mediated immune responses by disrupting the intricate network of signaling pathways that converge on CD2 activation. Resveratrol activates CD2 indirectly by modulating the NF-κB signaling pathway, enhancing CD2 transcriptional regulation. PD 0332991 (Palbociclib), a CDK 4/6 inhibitor, indirectly activates CD2 by modulating the cell cycle, influencing the expression dynamics of CD2. Honokiol modulates the NF-κB signaling pathway, providing an indirect mechanism for activating CD2-mediated immune responses by enhancing CD2 transcriptional regulation. Plerixafor (AMD3100), a CXCR4 antagonist, activates CD2 indirectly by influencing chemokine signaling, modulating the interactions between CD2 and its ligands. These CD2 activators offer valuable tools for unraveling the complexities of CD2-related cellular processes, shedding light on the specific molecular events regulated by CD2 and its interconnected signaling pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $115.00 $337.00 | 3 | |
Betulinic Acid, a pentacyclic triterpenoid, can activate CD2 indirectly by modulating the NF-κB signaling pathway. It promotes the degradation of IκBα, leading to the release and translocation of NF-κB into the nucleus. NF-κB activation, in turn, influences the expression of genes involved in T cell activation, including CD2. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $180.00 $726.00 $1055.00 $3350.00 $5200.00 | 23 | |
A769662, an AMP-activated protein kinase (AMPK) activator, directly influences CD2 activation by modulating AMPK-dependent pathways. Activation of AMPK by A769662 leads to the inhibition of mTOR, a key regulator of T cell activation. The downstream effects include modulation of CD2-mediated immune responses, as mTOR is intricately linked to CD2 signaling. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $94.00 $348.00 | 69 | |
BML-275, also known as Dorsomorphin, is an AMP-activated protein kinase (AMPK) activator that influences CD2 indirectly. Activation of AMPK by BML-275 inhibits mTOR, a key regulator of T cell activation. The downstream effects include modulation of CD2-mediated immune responses, as mTOR is intricately linked to CD2 signaling. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, a natural polyphenol, can activate CD2 indirectly by modulating the NF-κB signaling pathway. It inhibits IκBα phosphorylation, preventing its degradation and the subsequent nuclear translocation of NF-κB. This modulation of NF-κB signaling influences the expression of genes involved in T cell activation, including CD2. | ||||||
2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester | 305834-79-1 | sc-479756 | 25 mg | $380.00 | ||
This compound, also called SC79, directly influences CD2 activation by modulating Akt-dependent pathways. Activation of Akt by SC79 enhances T cell activation and function, events tightly regulated by CD2. The specific activation of Akt by SC79 provides a direct mechanism for influencing CD2 function by targeting a key kinase involved in the intricate network of signaling pathways regulating CD2. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR, an AMP-activated protein kinase (AMPK) activator, directly influences CD2 activation by modulating AMPK-dependent pathways. Activation of AMPK by AICAR leads to the inhibition of mTOR, a key regulator of T cell activation. The downstream effects include modulation of CD2-mediated immune responses, as mTOR is intricately linked to CD2 signaling. | ||||||
GSK 690693 | 937174-76-0 | sc-363280 sc-363280A | 10 mg 50 mg | $255.00 $1071.00 | 4 | |
GSK690693, an Akt activator, directly influences CD2 activation by modulating Akt-dependent pathways. Activation of Akt by GSK690693 enhances T cell activation and function, events tightly regulated by CD2. The specific activation of Akt by GSK690693 provides a direct mechanism for influencing CD2 function by targeting a key kinase involved in the intricate network of signaling pathways regulating CD2. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
2-Deoxy-D-glucose (2-DG) activates CD2 indirectly by modulating the AMP-activated protein kinase (AMPK) signaling pathway. It interferes with glucose metabolism, leading to AMPK activation. The downstream effects include inhibition of mTOR, a key regulator of T cell activation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a natural polyphenol, activates CD2 indirectly by modulating the NF-κB signaling pathway. It inhibits IκBα phosphorylation, preventing its degradation and the subsequent nuclear translocation of NF-κB. This modulation of NF-κB signaling influences the expression of genes involved in T cell activation, including CD2. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $315.00 | ||
PD 0332991 (Palbociclib), a cyclin-dependent kinase (CDK) 4/6 inhibitor, indirectly activates CD2 by modulating the cell cycle. Inhibition of CDK4/6 by PD 0332991 arrests the cell cycle, leading to increased CD2 expression during the G1 phase. The modulation of the cell cycle by PD 0332991 provides an indirect mechanism for activating CD2-mediated immune responses by influencing the expression dynamics of CD2. | ||||||