CD164L2 Activators
CD164L2 Activators constitute a group of compounds that enhance the functional activity of CD164L2 through specific interactions with signaling pathways or biological processes. These activators are not merely general enhancers of cellular activity but are involved in precise mechanisms that upregulate the functional role of CD164L2. For instance, EGF activates the EGFR, which leads to the stimulation of the Ras/Raf/MEK/ERK pathway, a key regulator of the cellular functions that CD164L2 is known to influence. Similarly, insulin, through its receptor, initiates a cascade that activates the PI3K/Akt signaling pathway, which is pivotal for various cellular functions including those associated with CD164L2. In this way, the activation of these pathways by insulin can augment CD164L2's functional activity.
On the other hand, compounds like hydrogen peroxide may modulate CD164L2 activity through oxidative stress mechanisms, which are known to affect signaling pathways such as MAPK; these pathways regulatethe activities of CD164L2. Ionomycin, by altering intracellular calcium levels, can activate calcium-dependent signaling mechanisms and enhance CD164L2's role in those processes. PMA triggers PKC, which phosphorylates proteins that can regulate the functional activity of CD164L2, thus directly enhancing its role in signaling. Forskolin raises cAMP levels, activating PKA, which can phosphorylate regulatory proteins associated with CD164L2, amplifying its functional activity in the cell. Sphingosine-1-phosphate operates through G-protein coupled receptors to activate signaling pathways, such as PI3K/Akt and MAPK/ERK, which are implicated in the modulation of CD164L2's role.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin receptor activation leads to the phosphorylation of insulin receptor substrates (IRS) which can then activate PI3K/Akt signaling pathway. The PI3K/Akt pathway is crucial for many cellular processes including those involving CD164L2, thereby enhancing CD164L2's functional activity. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
As a reactive oxygen species, hydrogen peroxide can modulate intracellular signaling pathways such as the MAPK pathway, which is known to regulate the processes in which CD164L2 is involved, leading to the functional activation of CD164L2. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
By increasing intracellular calcium levels, ionomycin activates calcium/calmodulin-dependent protein kinase (CaMK) pathways. CD164L2, being involved in calcium-dependent cellular processes, has its activity enhanced by the activation of these pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), which phosphorylates target proteins that can interact with or regulate CD164L2. Activation of PKC can thus enhance the functional activity of CD164L2 by promoting its involvement in cellular signaling. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin stimulates adenylyl cyclase, increasing cAMP levels and subsequently activating PKA. PKA can phosphorylate proteins that interact with CD164L2, enhancing its functional activity in cellular signaling processes. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
S1P binds to its G-protein coupled receptors, which can activate downstream signaling pathways such as PI3K/Akt and MAPK/ERK that are known to modulate cellular processes in which CD164L2 is implicated, thus enhancing CD164L2's functional activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is an inhibitor of PI3K, which can disrupt the PI3K/Akt pathway leading to compensatory mechanisms that may enhance the functional signaling processes involving CD164L2. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
By inhibiting the TGF-β receptor, SB431542 can modulate the SMAD signaling pathway, which may have downstream effects on cellular processes that involve CD164L2, leading to its enhanced functional activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, which is involved in the PI3K/Akt pathway. This inhibition can lead to the activation of alternative pathways that involve CD164L2, enhancing its functional activity as a result of compensatory cellular signaling. | ||||||