Date published: 2025-12-19

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CCK Inhibitors

Cholecystokinin (CCK) inhibitors are a class of chemical compounds that primarily target the cholecystokinin system within the human body. Cholecystokinin is a peptide hormone and neuropeptide that plays a crucial role in the gastrointestinal system, particularly in the regulation of digestion and appetite. It is released by cells in the small intestine and acts on various receptors throughout the body. CCK inhibitors are designed to interfere with the activity of cholecystokinin, modulating its effects in various physiological processes. Cholecystokinin is primarily known for its role in stimulating the release of digestive enzymes and bile from the pancreas and gallbladder, respectively, in response to the presence of fats and proteins in the small intestine. This hormone also plays a role in appetite regulation by signaling feelings of fullness and satiety to the brain. CCK inhibitors, therefore, function by blocking or reducing the activity of cholecystokinin, which can have diverse effects on the digestive system and appetite regulation. They impact the rate of digestion, nutrient absorption, and overall energy balance. The development and study of CCK inhibitors contribute to our understanding of the complex mechanisms involved in gastrointestinal physiology and appetite regulation, which may have implications in various aspects of health and well-being.

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Items 1 to 10 of 13 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Devazepide

103420-77-5sc-203562
sc-203562A
5 mg
50 mg
$245.00
$1030.00
1
(1)

Devazepide acts as a selective antagonist of the CCK-B receptor, influencing various neuroendocrine pathways. Its unique structure allows for specific binding interactions that inhibit receptor activation, thereby modulating downstream signaling events. The compound demonstrates a distinct affinity profile, leading to competitive inhibition that alters physiological responses. Its stability in biological systems contributes to its effectiveness in regulating peptide-mediated signaling without rapid degradation.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

Dexamethasone is a synthetic glucocorticoid that can modulate inflammatory responses and alter gene expression, potentially leading to a decrease in CCK production.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin is an immunosuppressive agent that can inhibit mTOR signaling, which may be involved in the regulation of CCK expression.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002 is a PI3 kinase inhibitor that can disrupt various intracellular signaling pathways, potentially affecting CCK expression.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

PD98059 is an MEK inhibitor that can inhibit the MAPK/ERK pathway, which may play a role in regulating CCK expression.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

SB203580 is a p38 MAP kinase inhibitor that can disrupt intracellular signaling and possibly lead to reduced CCK expression.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

SP600125 is a JNK inhibitor that can alter cellular signaling and potentially impact the expression of CCK.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Wortmannin is a potent inhibitor of PI3 kinase that can disrupt various signaling pathways, potentially affecting CCK expression.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein is an isoflavone that can act as a tyrosine kinase inhibitor and may have an effect on signaling pathways regulating CCK expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin is a natural compound found in turmeric, which has been shown to modulate various cellular processes, potentially impacting CCK expression.