CCDC56 activators encompass a group of diverse chemical compounds that indirectly promote the functional activity of CCDC56 through a variety of signaling pathways. The adenylate cyclase stimulator Forskolin and the phosphodiesterase inhibitor IBMX enhance CCDC56's potential roles in signal transduction by increasing intracellular cAMP levels, thereby activating protein kinase A (PKA) which may phosphorylate proteins that interact with CCDC56. Similarly, PMA activates protein kinase C (PKC) and could lead to the phosphorylation of substrates that modulate CCDC56's activity within cellular signaling networks.
CCDC56 activators comprise a spectrum of chemical compounds that indirectly stimulate the functional activity of CCDC56 through distinct signaling pathways. Forskolin and IBMX operate by elevating intracellular cAMP levels, which activates protein kinase A (PKA), potentially leading to the phosphorylation of proteins that interact with or regulate CCDC56's function in signal transduction. PMA, as a potent activator of protein kinase C (PKC), may alter CCDC56's activity by modifying phosphorylation patterns of proteins within the cellular milieu that CCDC56 may influence. Sphingosine-1-phosphate engages G-protein-coupled receptors, initiating signaling cascades that could intersect with CCDC56's role, potentially enhancing its activity by modulating cytoskeletal dynamics or vesicular trafficking, while A23187 raises intracellular calcium, activating calcium-dependent signaling that could intersect with CCDC56's function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylyl cyclase, leading to an increase in cyclic AMP (cAMP) levels. Elevated cAMP activates PKA, which can phosphorylate various proteins and potentially enhance CCDC56 function in signal transduction. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX is a nonspecific inhibitor of phosphodiesterases, which prevents the breakdown of cAMP and cGMP, leading to their accumulation. This can indirectly enhance CCDC56 activity by amplifying cAMP-dependent signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a PKC activator, which can lead to downstream effects on cellular processes that may include the functional activation of CCDC56 by phosphorylation or by changing the cellular context in which CCDC56 operates. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
This lipid signaling molecule activates G-protein coupled receptors, leading to downstream effects that could indirectly enhance the activity of CCDC56 through altered cytoskeletal dynamics or vesicular trafficking. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
Okadaic Acid is a potent inhibitor of protein phosphatases 1 and 2A, leading to increased phosphorylation levels of proteins within the cell, which may indirectly enhance the functional activity of CCDC56 through this mechanism. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 is an ionophore that increases intracellular calcium levels, potentially enhancing CCDC56 functional activity by activating calcium-dependent signaling pathways that could intersect with CCDC56's role in the cell. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is a known inhibitor of various protein kinases and has antioxidant properties. It could indirectly enhance CCDC56 activity by modulating signaling pathways that intersect with the functions of CCDC56. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor, leading to increased cytosolic calcium levels. This elevation in calcium may enhance CCDC56 activity indirectly by affecting calcium-dependent signaling pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is another PI3K inhibitor, which by altering the PI3K/AKT pathway, may enhance the activity of CCDC56 by affecting related signaling cascades and cellular processes. | ||||||