CCDC52 Activators
CCDC52 Activators encompass a diverse group of chemical compounds that indirectly enhance the functional activity of CCDC52 through various specific signaling pathways. Compounds such as Forskolin and Epigallocatechin gallate (EGCG) elevate intracellular messengers like cAMP or inhibit protein kinases, respectively, which can lead to the enhanced functional activity of CCDC52 by altering the phosphorylation state of proteins within CCDC52-regulated pathways. Similarly, Sphingosine-1-phosphate and Thapsigargin work by modulating lipid signaling and disrupting calcium homeostasis, which could activate downstream pathways that CCDC52 is involved in. The protein kinase C activator PMA and the tyrosine kinase inhibitor Genistein also contribute by either directly enhancing signaling pathways or decreasing competitive kinase signaling, benefiting CCDC52's role within the cell.
Furthermore, the functional activity of CCDC52 is influenced by compounds that target specific aspects of intracellular signaling. LY294002 and Wortmannin, both PI3K inhibitors, are likely to indirectly augment CCDC52's role by modulating pathways that are under PI3K's influence. MEK inhibitor U0126 and p38 MAPK inhibitor SB203580 could shift the balance of cellular signaling in a way that benefits CCDC52-involved processes. A23187, by increasing intracellular calcium, may activate calcium-dependent proteins and pathways where CCDC52 functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing intracellular cAMP levels. Elevated cAMP enhances CCDC52 by activating PKA, which likely phosphorylates proteins in pathways where CCDC52 is involved. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This polyphenol inhibits several protein kinases, which could reduce negative regulation on pathways involving CCDC52, thereby indirectly increasing its functional activity. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
By modulating sphingolipid signaling, sphingosine-1-phosphate could enhance CCDC52 activity indirectly through its involvement in membrane-associated signaling events. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin disrupts calcium homeostasis, potentially enhancing CCDC52 function by activating calcium-dependent signaling pathways that impinge on processes CCDC52 regulates. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
As a broad kinase inhibitor, staurosporine may lead to the selective enhancement of CCDC52's activity by reducing kinase-mediated inhibition on related signaling cascades. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
By inhibiting PI3K, LY294002 could indirectly enhance CCDC52's function in pathways negatively regulated by PI3K activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
By inhibiting p38 MAPK, SB203580 may indirectly enhance CCDC52's role in stress response pathways. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
As a tyrosine kinase inhibitor, Genistein could help to enhance CCDC52's functional activity by reducing competitive signaling through tyrosine kinases. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
This ionophore increases intracellular calcium levels, likely enhancing CCDC52's activity by activating downstream calcium-dependent processes. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin, another PI3K inhibitor, could indirectly enhance CCDC52's activity by modulating signaling pathways regulated by PI3K. | ||||||