CCDC122 Inhibitors
CCDC122 inhibitors, as per the compounds listed, are chemicals that can diminish the functional activity of the CCDC122 protein by targeting various signaling pathways it may be involved in. Staurosporine, Wortmannin, LY294002, and Y-27632, for instance, inhibit protein kinases, PI3Ks, and Rho-associated protein kinases respectively. These are all key elements in different signaling pathways that contribute to protein functionality. Inhibition of these components can consequently lead to the disruption of downstream protein activity.
Meanwhile, PD98059, Rapamycin, SP600125, SB203580, U0126, BAY 11-7082, Cyclopamine, and ZM 336372 target specific pathways such as MAPK/ERK, mTOR, JNK, p38 MAPK, NF-kB activation, Hedgehog, and Raf/MEK/ERK respectively. These pathways play pivotal roles in different cellular processes.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent protein kinase inhibitor. It can inhibit the phosphorylation process in signaling pathways, potentially impacting the downstream proteins like CCDC122. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A covalent inhibitor of phosphoinositide 3-kinases (PI3Ks), which are involved in multiple signaling pathways. By inhibiting PI3Ks, downstream proteins could be affected. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another inhibitor of PI3Ks, it can potentially interfere with the activity of proteins downstream in the signaling pathway. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A selective inhibitor of ROCK (Rho-associated protein kinase), part of the Rho pathway which is involved in cell movement and morphology. If CCDC122 is part of this pathway, this inhibitor could affect its function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An inhibitor of MEK, which is part of the MAPK signaling pathway. This could potentially affect proteins downstream in the pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An inhibitor of mTOR (mammalian target of Rapamycin), a central regulator of cell growth and proliferation. This could potentially affect proteins involved in these processes. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A selective inhibitor of JNK (c-Jun N-terminal Kinases), which are involved in a wide range of cellular processes. This could potentially affect the activity of proteins downstream in the pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
An inhibitor of p38 MAPK, another pathway associated with a wide range of cellular processes. This inhibitor could potentially affect proteins downstream in the pathway. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Inhibitor of NF-kB activation, which could potentially affect numerous proteins downstream in the pathway. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
Inhibitor of the Hedgehog signaling pathway, potentially affecting downstream proteins. | ||||||