CCDC113 Inhibitors
These inhibitors have various targets within the cell, affecting different aspects of cellular functions that could indirectly influence CCDC113's activity or its interaction with other cellular components. Nocodazole and paclitaxel have opposing effects on microtubules: while nocodazole disrupts microtubules, paclitaxel stabilizes them. Both actions can alter the dynamics of the cytoskeleton and potentially impact proteins that interact with microtubules. Monensin and Brefeldin A affect vesicular trafficking, with Monensin altering ion gradients crucial for vesicle formation and Brefeldin A inhibiting protein transport between the ER and Golgi, thereby affecting protein processing and trafficking.
Cytochalasin D and Latrunculin A target the actin cytoskeleton. Cytochalasin D binds to the barbed ends of actin filaments, preventing elongation, whereas Latrunculin A sequesters actin monomers. ML-7 and Y-27632 inhibit kinases involved in cytoskeletal dynamics and cellular motility, which can have downstream effects on proteins involved in these processes. Dynasore offers a more targeted approach by inhibiting dynamin, a GTPase that mediates vesicular scission during endocytosis, directly affecting vesicular trafficking.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
A microtubule depolymerizer that can disrupt microtubule dynamics, potentially affecting proteins associated with the cytoskeleton. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules and can prevent their disassembly, thereby impacting proteins that interact with the microtubule network. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
An ionophore that disrupts intracellular ion gradients and can affect vesicular trafficking and protein transport. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Inhibits protein transport between the endoplasmic reticulum and Golgi apparatus, potentially affecting proteins involved in trafficking. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Disrupts actin filament polymerization and can affect proteins involved in maintaining cytoskeletal integrity. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Binds to actin monomers and inhibits their polymerization, affecting proteins associated with the actin cytoskeleton. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Inhibits myosin light chain kinase (MLCK) and can affect cellular contraction and motility processes. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Inhibits ROCK kinase, potentially affecting cell shape and motility, which could alter the function of proteins involved in these processes. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
A dynamin inhibitor that can inhibit vesicular scission, potentially affecting vesicular trafficking and protein localization. | ||||||
Mdivi-1 | 338967-87-6 | sc-215291 sc-215291B sc-215291A sc-215291C | 5 mg 10 mg 25 mg 50 mg | $67.00 $126.00 $251.00 $465.00 | 13 | |
Inhibits mitochondrial division and can indirectly influence cellular energy states and associated protein functions. | ||||||