CCDC113 Activators
Retinoic Acid and Lithium Chloride can drive changes in gene expression profiles and signaling pathways, such as Wnt, that are essential for ciliogenesis, thus affecting proteins associated with cilia, including CCDC113. Forskolin, through the elevation of cAMP, and Rapamycin, by inhibiting mTOR, can also modulate processes essential for ciliary structure maintenance, which is crucial for the function of ciliary proteins. Chloroquine and Cytochalasin D can impact the autophagy-lysosomal pathway and cytoskeletal organization, respectively, both of which are important for proper ciliary function and may thereby impact CCDC113.
Ciliobrevin D, by inhibiting Hedgehog signaling, and Roscovitine, through the inhibition of CDKs, can affect ciliogenesis. ZM-447439 and CP110, which inhibit Aurora kinases and block centriole duplication, respectively, can alter the assembly and maintenance of cilia, potentially affecting CCDC113.Bafilomycin A1 and Y-27632 interfere with vacuolar acidification and cytoskeletal dynamics, both of which are important for ciliary function and could, in turn, impact the activity of CCDC113.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influences gene expression and is known to regulate ciliogenesis, which can affect the function of ciliary proteins including CCDC113. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Inhibits GSK-3β and can activate Wnt signaling, which plays a role in ciliogenesis and could influence CCDC113. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Elevates cAMP levels and activates PKA, potentially affecting ciliary structure and proteins like CCDC113. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor, which can affect ciliogenesis and autophagy, processes potentially connected to CCDC113 function. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Modulates autophagy and lysosomal function, which are linked to ciliary function and thereby could influence CCDC113. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Actin polymerization inhibitor, affecting cytoskeletal organization and potentially ciliary function, impacting CCDC113. | ||||||
Ciliobrevin D | 1370554-01-0 | sc-507482 | 10 mg | $413.00 | ||
Hedgehog signaling pathway inhibitor that can disrupt ciliogenesis and potentially alter CCDC113 activity. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
CDK inhibitor, which can affect cell cycle regulation and ciliogenesis, potentially influencing CCDC113 activity. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
Aurora kinase inhibitor, affects cell division and ciliogenesis, and could alter the functional status of CCDC113. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
Inhibitor of vacuolar H+-ATPase, affects acidification and trafficking to the cilia, processes that can influence CCDC113. | ||||||