CB1 Inhibitors
Items 11 to 20 of 22 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
NIDA-41020 | 502486-89-7 | sc-253189 | 10 mg | $185.00 | ||
NIDA-41020 is a potent CB1 receptor modulator characterized by its unique ability to stabilize receptor dimers, enhancing signal transduction efficiency. Its specific molecular interactions involve hydrogen bonding and hydrophobic contacts, which facilitate a conformational shift in the receptor. The compound exhibits a distinctive pharmacokinetic profile, with a prolonged half-life that allows for sustained receptor engagement, potentially influencing downstream metabolic pathways and cellular homeostasis. | ||||||
Org 27569 | 868273-06-7 | sc-204151 sc-204151A | 10 mg 50 mg | $164.00 $689.00 | ||
Org27569 is a CB1 receptor antagonist/inverse agonist that has been investigated for its potential use in obesity. | ||||||
(S)-SLV 319 | 464213-10-3 | sc-222285 sc-222285A | 1 mg 5 mg | $92.00 $311.00 | ||
(S)-SLV 319 is a selective CB1 receptor antagonist that exhibits unique allosteric modulation properties. Its binding induces a conformational change in the receptor, altering the dynamics of ligand-receptor interactions. This compound demonstrates rapid kinetics, allowing for swift receptor desensitization. Additionally, its distinct hydrophobic regions enhance membrane permeability, influencing its distribution and interaction with lipid bilayers, which may affect cellular signaling cascades. | ||||||
(±)-SLV 319 | 362519-49-1 | sc-222317 sc-222317A | 1 mg 5 mg | $30.00 $131.00 | ||
(±)-SLV 319 acts as a CB1 receptor modulator, showcasing intriguing competitive binding characteristics. Its stereochemistry allows for differential interaction with receptor subtypes, potentially influencing downstream signaling pathways. The compound's unique structural features facilitate specific hydrogen bonding and hydrophobic interactions, enhancing its affinity. Furthermore, its ability to stabilize receptor conformations may lead to altered signaling dynamics, impacting cellular responses in complex environments. | ||||||
URB447 | 1132922-57-6 | sc-224347 sc-224347A | 5 mg 10 mg | $132.00 $250.00 | ||
URB447 is a selective CB1 receptor antagonist that exhibits unique allosteric modulation properties. Its distinct molecular architecture enables it to engage in specific electrostatic interactions with receptor sites, influencing conformational dynamics. The compound's kinetic profile suggests a rapid association and dissociation with the receptor, allowing for nuanced regulation of signaling pathways. Additionally, its lipophilic characteristics enhance membrane permeability, potentially affecting bioavailability and receptor accessibility. | ||||||
rac-Falcarinol | 4117-12-8 | sc-396040 | 1 mg | $430.00 | ||
Rac-Falcarinol is a compound that interacts with the CB1 receptor through unique hydrophobic and hydrogen bonding interactions, influencing receptor conformation and activity. Its structural features facilitate specific binding dynamics, leading to distinct modulation of signaling pathways. The compound's stereochemistry plays a crucial role in its interaction kinetics, allowing for selective engagement with receptor subtypes. Furthermore, its solubility properties may impact its distribution within biological membranes, affecting overall receptor interaction. | ||||||
CB-25 | 869376-63-6 | sc-204675 sc-204675A | 1 mg 5 mg | $24.00 $108.00 | ||
CB-25 is a compound notable for its intricate molecular interactions with the CB1 receptor, showcasing a unique ability to stabilize receptor conformations. Its structural features facilitate specific hydrogen bonding and hydrophobic interactions, which enhance its binding efficacy. The compound's reactivity profile is influenced by its functional groups, allowing for rapid modulation of downstream signaling pathways. Additionally, its solubility characteristics may influence membrane permeability, impacting its overall biological activity. | ||||||
O-1821 | 35482-50-9 | sc-205417 sc-205417A | 1 mg 5 mg | $31.00 $121.00 | ||
O-1821 exhibits remarkable selectivity for the CB1 receptor, characterized by its ability to induce allosteric modulation. This compound engages in unique π-π stacking interactions with aromatic residues, enhancing receptor affinity. Its kinetic profile reveals a rapid onset of action, attributed to its efficient conformational changes upon binding. Furthermore, O-1821's lipophilic nature promotes significant membrane integration, potentially altering receptor localization and signaling dynamics. | ||||||
AVE-1625 | 358970-97-5 | sc-221277 sc-221277A | 1 mg 5 mg | $64.00 $288.00 | ||
AVE-1625 is a compound characterized by its selective binding affinity for the CB1 receptor, driven by unique electrostatic interactions and conformational adaptability. Its molecular structure promotes specific ligand-receptor dynamics, enhancing its ability to modulate intracellular signaling cascades. The compound exhibits distinct reaction kinetics, influenced by its steric configuration, which may alter its interaction with lipid bilayers, thereby affecting its bioavailability and receptor engagement. | ||||||
Rimonabant Hydrochloride | 158681-13-1 | sc-212786 | 10 mg | $163.00 | 1 | |
Rimonabant Hydrochloride is a potent antagonist of the CB1 receptor, demonstrating a unique binding affinity that disrupts endocannabinoid signaling. Its structure allows for specific hydrogen bonding with key amino acid residues, influencing receptor conformation. The compound exhibits a distinctive pharmacokinetic profile, with a prolonged half-life that facilitates sustained interaction. Additionally, its hydrophobic characteristics enhance its interaction with lipid membranes, potentially affecting receptor clustering and downstream signaling pathways. | ||||||