CB1 Inhibitors
Items 1 to 10 of 22 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MAFP | 188404-10-6 | sc-203440 | 5 mg | $215.00 | 4 | |
MAFP is a potent CB1 receptor antagonist characterized by its unique acyl chain that facilitates hydrophobic interactions, enhancing binding affinity. Its structural conformation allows for selective engagement with receptor sites, influencing downstream signaling cascades. The compound's reactivity as an acid halide promotes rapid esterification reactions, which can alter its interaction kinetics. Furthermore, MAFP's lipophilicity aids in its diffusion across cellular membranes, impacting its bioavailability and functional dynamics. | ||||||
NESS 0327 | 494844-07-4 | sc-222054 sc-222054A | 1 mg 5 mg | $316.00 $1270.00 | 1 | |
NESS 0327 is a selective CB1 receptor modulator distinguished by its unique functional groups that enable specific hydrogen bonding interactions, enhancing receptor affinity. Its conformational flexibility allows for tailored engagement with the receptor, influencing various intracellular signaling pathways. As an acid halide, NESS 0327 exhibits high reactivity, facilitating rapid acylation processes that can significantly affect its kinetic profile and interaction with biological targets. | ||||||
Rimonabant | 168273-06-1 | sc-205491 sc-205491A | 5 mg 10 mg | $72.00 $160.00 | 15 | |
Rimonabant is a well-known CB1 inhibitor that was previously used for weight management. However, it has been withdrawn from the market due to safety concerns. | ||||||
AM-251 | 183232-66-8 | sc-200366A sc-200366 sc-200366B sc-200366C | 5 mg 10 mg 50 mg 100 mg | $71.00 $143.00 $612.00 $847.00 | 4 | |
AM-251 is a selective antagonist of the CB1 receptor, characterized by its unique structural features that promote specific hydrophobic interactions, enhancing binding efficacy. Its rigid molecular framework restricts conformational changes, leading to a stable receptor complex. This stability influences downstream signaling cascades, while its reactivity as an acid halide allows for efficient acylation, impacting its kinetic behavior and interactions with various biomolecules. | ||||||
LY-320135 | 176977-56-3 | sc-204066 sc-204066A | 10 mg 50 mg | $175.00 $739.00 | ||
LY-320135 is a selective CB1 receptor antagonist distinguished by its unique ability to form hydrogen bonds with key amino acid residues, enhancing its binding affinity. The compound's flexible molecular structure allows for dynamic conformational adjustments, facilitating optimal receptor engagement. Its reactivity as an acid halide enables rapid acylation reactions, influencing its interaction kinetics and modulating downstream signaling pathways in complex biological systems. | ||||||
AM 281 | 202463-68-1 | sc-202050 sc-202050A | 1 mg 5 mg | $31.00 $82.00 | 5 | |
AM 281 is a selective CB1 receptor antagonist characterized by its unique hydrophobic interactions with the receptor's binding pocket, which stabilize its conformation for enhanced affinity. The compound exhibits a distinctive electronic distribution that influences its reactivity, allowing for specific interactions with nearby residues. Its kinetic profile reveals a rapid onset of action, impacting receptor desensitization and internalization processes, thereby modulating cellular responses effectively. | ||||||
MJ 15 | 944154-76-1 | sc-361252 sc-361252A | 10 mg 50 mg | $179.00 $756.00 | ||
MJ 15 is a potent CB1 receptor modulator distinguished by its unique steric hindrance, which facilitates selective binding to the receptor's allosteric site. This compound exhibits a remarkable ability to alter receptor conformational dynamics, enhancing signal transduction pathways. Its lipophilic nature promotes membrane permeability, influencing the kinetics of receptor activation and subsequent downstream effects on neuronal signaling. The compound's specific molecular interactions contribute to its nuanced regulatory role in cellular processes. | ||||||
Amauromine | 88360-87-6 | sc-391052 | 1 mg | $180.00 | ||
Amauromine is a selective CB1 receptor antagonist characterized by its unique structural conformation, which allows for specific interactions with the receptor's binding site. This compound exhibits a distinct ability to stabilize inactive receptor states, thereby modulating downstream signaling pathways. Its hydrophobic characteristics enhance its affinity for lipid membranes, influencing the kinetics of receptor-ligand interactions and altering the overall dynamics of cannabinoid signaling in neural tissues. | ||||||
AM 404 | 183718-77-6 | sc-207275 | 10 mg | $118.00 | ||
AM 404 is a potent CB1 receptor modulator known for its unique ability to disrupt endocannabinoid reuptake, thereby enhancing the availability of endogenous cannabinoids. Its molecular structure facilitates strong hydrophobic interactions with lipid bilayers, promoting effective membrane penetration. This compound exhibits rapid kinetics in receptor binding, leading to significant alterations in neurotransmitter release and synaptic plasticity, ultimately influencing neural communication pathways. | ||||||
Virodhamine hydrochloride | 443129-35-9 | sc-202853 | 5 mg | $131.00 | ||
Virodhamine hydrochloride is a selective CB1 receptor antagonist that exhibits unique allosteric modulation, influencing receptor conformation and activity. Its distinct hydrophilic and lipophilic balance allows for effective interaction with membrane proteins, enhancing its binding affinity. The compound demonstrates notable reaction kinetics, with a rapid onset of action that alters intracellular signaling cascades. This modulation can lead to significant changes in cellular responses, impacting various physiological processes. | ||||||