CAP-18 Inhibitors
CAP-18 inhibitors belong to a specific chemical class of molecules designed to target and modulate the activity of CAP-18, also known as cathelicidin antimicrobial peptide 18. CAP-18 is a naturally occurring antimicrobial peptide found in various tissues of the human body, including the skin, respiratory tract, and gastrointestinal system. Its primary function is to serve as a part of the innate immune system, playing a crucial role in defending the body against microbial infections. CAP-18 inhibitors are synthetic or naturally derived compounds that are engineered to interfere with the function of CAP-18, either by blocking its activity or altering its conformation.
These inhibitors are designed to act at the molecular level, often by binding to specific sites on CAP-18, which can lead to the inhibition of its antimicrobial properties. By targeting CAP-18, these inhibitors may have potential applications in various fields, such as microbiology and immunology research. Researchers are particularly interested in CAP-18 inhibitors as they offer a means to explore the role of CAP-18 in host defense mechanisms and gain a deeper understanding of its interactions with microbial pathogens. Overall, CAP-18 inhibitors represent a promising avenue for scientific inquiry into the innate immune system and its potential impact on microbial infections.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hydrocortisone | 50-23-7 | sc-300810 | 5 g | $102.00 | 6 | |
A glucocorticoid that can reduce inflammation and modulate immune responses, leading to decreased expression of antimicrobial peptides including CAP-18. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Similar to hydrocortisone, this glucocorticoid can suppress inflammation and might reduce CAP-18 levels as part of its broad anti-inflammatory effects. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
A flavonoid that can modulate various signaling pathways and might alter the expression of immune-related genes, including those related to CAP-18. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound found in turmeric with broad biological effects, which may include the modulation of inflammatory pathways and possible downregulation of antimicrobial peptides like CAP-18. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
The main catechin in green tea, known to have anti-inflammatory effects, and can modulate immune responses, potentially affecting CAP-18 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenol from red wine that can influence inflammation and immune function, which may in turn impact CAP-18 levels. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can affect immune cell function and might lead to changes in the expression of antimicrobial peptides including CAP-18. | ||||||
Mycophenolate mofetil | 128794-94-5 | sc-200971 sc-200971A | 20 mg 100 mg | $37.00 $109.00 | 1 | |
An immunosuppressant that can decrease the production of antibodies and potentially alter the expression of peptides like CAP-18. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
An immunosuppressive drug that can reduce inflammation and may lead to a decrease in CAP-18 expression through its broad immune-modulating effects. | ||||||