C3orf24 Inhibitors
C3orf24 inhibitors belong to a specific category of chemical compounds designed to target and modulate the activity of the C3orf24 protein. C3orf24, short for Chromosome 3 Open Reading Frame 24, is a relatively less understood protein that has garnered increasing attention in the realm of molecular biology and cellular research. Inhibitors of this protein are designed to interfere with its normal function or activity within the cell. C3orf24 is thought to play a role in various cellular processes, and inhibiting it can be a valuable tool for researchers aiming to unravel its precise functions and implications in different biological contexts.
These inhibitors are typically small molecules or compounds that are synthesized to interact with C3orf24 specifically, either by blocking its active site or by binding to it in such a way that it disrupts its normal cellular functions. The development and utilization of C3orf24 inhibitors are critical for advancing our understanding of the protein's biological significance. Researchers use these inhibitors in laboratory settings to investigate the downstream effects of inhibiting C3orf24, shedding light on its involvement in processes such as signal transduction, cell cycle regulation, or other cellular pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Cisplatin forms DNA adducts, leading to DNA damage that activates the DNA damage response, potentially suppressing FANCD2 expression as a part of cellular stress response. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
5-Fluorouracil disrupts DNA synthesis and repair processes, which may indirectly affect FANCD2 expression since it's involved in DNA damage repair and cell cycle regulation. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
Nutlin-3 inhibits the p53-MDM2 interaction, potentially leading to p53 activation. As FANCD2 expression can be negatively regulated by p53, Nutlin-3 may suppress FANCD2 expression indirectly. | ||||||
Auranofin | 34031-32-8 | sc-202476 sc-202476A sc-202476B | 25 mg 100 mg 2 g | $150.00 $210.00 $1899.00 | 39 | |
Auranofin is a thioredoxin reductase inhibitor. Reduced thioredoxin is involved in FANCD2 activation, so inhibiting thioredoxin reductase may hinder FANCD2 activation and, consequently, its expression. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $315.00 | ||
PD-0332991 (Palbociclib) is a CDK4/6 inhibitor. By suppressing CDK4/6 activity, it can disrupt the cell cycle, potentially leading to reduced FANCD2 expression since it's involved in cell cycle regulation. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG-132 is a proteasome inhibitor. It may increase the stability of proteins that negatively regulate FANCD2 or degrade FANCD2 itself, thus potentially inhibiting FANCD2 expression. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
2-Deoxy-D-glucose interferes with glycolysis and may disrupt energy metabolism, which could indirectly affect FANCD2 expression since it's involved in DNA repair processes that require energy. | ||||||
AZD7762 | 860352-01-8 | sc-364423 | 2 mg | $107.00 | ||
AZD7762 is a Chk1 inhibitor. It disrupts cell cycle checkpoints and DNA repair processes. Inhibition of Chk1 may lead to reduced FANCD2 activation and expression since FANCD2 is involved in DNA repair checkpoints. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin is a topoisomerase I inhibitor that causes DNA damage. This DNA damage response could negatively affect FANCD2 expression since FANCD2 is involved in repairing DNA damage. | ||||||