Ankyrin repeat and ubiquitin domain containing 1 (ANKUB1) is a multifaceted protein characterized by the presence of distinct functional domains that suggest a role in molecular scaffolding and protein turnover regulation within the cell. The ankyrin repeat domain, a common protein-protein interaction motif, allows ANKUB1 to potentially engage in complex formation with various cellular partners, facilitating the assembly of protein complexes or mediating specific signaling cascades through such interactions.
The ubiquitin domain indicates a possible involvement in the ubiquitin-proteasome system (UPS), a critical pathway for protein degradation and turnover. This domain may bind to ubiquitinated proteins, acting as a shuttle or mediator that guides them to the proteasome for degradation. Alternatively, ANKUB1 itself may become ubiquitinated, thereby regulating its own stability or function within the cell.ANKUB1, with its dual-domain structure, might play an essential role in cellular processes such as signal transduction, cytoskeletal organization, or the maintenance of protein quality control. Its expression patterns and post-translational modifications could further refine its activity and specificity, enabling it to respond to cellular cues or stress conditions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin increases intracellular calcium levels. Elevated calcium can activate pathways that could intersect with the function of "Ankyrin repeat and ubiquitin domain containing 1". | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates PKC, which could phosphorylate substrates or alter cellular processes that are indirectly involved in the activation of "Ankyrin repeat and ubiquitin domain containing 1". | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor. By inhibiting PI3K, it can alter signaling cascades that may upregulate pathways involving "Ankyrin repeat and ubiquitin domain containing 1". | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, which might shift signaling towards pathways that activate "Ankyrin repeat and ubiquitin domain containing 1". | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 inhibits MEK1/2 leading to potential alterations in signaling pathways that could enhance the activity of "Ankyrin repeat and ubiquitin domain containing 1". | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG inhibits certain protein kinases and might activate signaling pathways that intersect with "Ankyrin repeat and ubiquitin domain containing 1" function. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is a tyrosine kinase inhibitor. By inhibiting these kinases, it could enhance pathways that activate "Ankyrin repeat and ubiquitin domain containing 1". | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Through modulation of sphingolipid signaling, this compound may influence pathways that activate "Ankyrin repeat and ubiquitin domain containing 1". | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin disrupts calcium homeostasis, potentially affecting calcium-dependent signaling pathways linked to "Ankyrin repeat and ubiquitin domain containing 1". | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a broad-spectrum PK inhibitor, which could selectively activate pathways related to "Ankyrin repeat and ubiquitin domain containing 1". | ||||||