C22orf25 Inhibitors
The protein known as "transport and golgi organization 2 homolog" (TANGO2) is part of a family of proteins implicated in the regulation of cellular transport and the structural organization of the Golgi apparatus. The Golgi apparatus is a critical organelle in the cell, primarily responsible for sorting and modifying proteins that are to be secreted or directed to different parts of the cell. TANGO2 plays a role in maintaining the functionality of the Golgi, ensuring that proteins are appropriately processed and trafficked.
TANGO2 is believed to interact with other proteins and components of the cell's transport machinery, facilitating the export of bulky cargoes from the endoplasmic reticulum (ER). This is particularly important for the secretion of large proteins or protein complexes, which require specialized handling to traverse the cellular infrastructure without causing traffic jams or damage to the cell.Mutations in the gene encoding TANGO2 have been associated with a rare genetic disorder known as TANGO2-related metabolic encephalopathy and arrhythmias.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A disrupts Golgi structure and function, which may indirectly influence TANGO2-related processes. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Monensin, an ionophore, alters Golgi apparatus function and can impact vesicular transport pathways involving TANGO2. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubules, impacting vesicular transport and potentially influencing TANGO2 activity. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Colchicine inhibits microtubule polymerization, affecting vesicular and organelle transport, which may impact TANGO2. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Dynasore inhibits dynamin, a GTPase involved in vesicular scission, potentially influencing TANGO2-related vesicular transport. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D inhibits actin polymerization, impacting cytoskeletal dynamics and potentially affecting TANGO2 function. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Latrunculin A disrupts actin filaments, influencing cytoskeletal organization and possibly impacting TANGO2. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, impacting protein processing in the ER and Golgi, which may influence TANGO2. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin inhibits phosphoinositide 3-kinases, potentially affecting vesicular trafficking and TANGO2 functions. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Vinblastine disrupts microtubule assembly, affecting cellular transport processes, potentially influencing TANGO2. | ||||||