C20orf26 Inhibitors
Cilia and flagella associated protein 61 (CFAP61) is a protein that, as its name suggests, is associated with the structure and function of cilia and flagella-hair-like organelles that protrude from the surface of many eukaryotic cells. Cilia and flagella are critical for a variety of cellular processes, including motility, fluid movement, sensing the cellular environment, and cell signaling.
CFAP61 is believed to be involved in the assembly or stability of the axonemal dynein arms, which are motor protein complexes that drive the bending and movement of cilia and flagella. The precise molecular function of CFAP61 is still under investigation, but it is postulated to be essential for the correct formation and maintenance of these organelles. Mutations in the gene encoding CFAP61 have been linked to ciliopathies, a group of disorders characterized by defective cilia formation or function. These diseases can manifest in a variety of ways, as cilia are ubiquitous across different tissue types and play multifaceted roles in organismal development and function. For instance, defective ciliary movement due to disruptions in CFAP61 may result in respiratory issues, infertility, or problems with the sensory systems, highlighting its importance across multiple physiological systems.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ciliobrevin D | 1370554-01-0 | sc-507482 | 10 mg | $413.00 | ||
Ciliobrevin D, a dynein motor inhibitor, might indirectly influence CFAP61 by affecting ciliary and flagellar motility. | ||||||
Tozasertib | 639089-54-6 | sc-358750 sc-358750A | 25 mg 50 mg | $62.00 $87.00 | 4 | |
Aurora kinase inhibitors like VX-680 could indirectly impact CFAP61 by modulating cellular processes related to cilia and flagella. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A may indirectly affect CFAP61 through its role in chromatin remodeling and gene expression, potentially impacting cilia and flagella dynamics. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an mTOR inhibitor, might indirectly influence CFAP61 by affecting cellular signaling pathways related to cilia and flagella formation and maintenance. | ||||||
Vismodegib | 879085-55-9 | sc-396759 sc-396759A | 10 mg 25 mg | $82.00 $158.00 | 1 | |
Vismodegib, a Hedgehog signaling pathway inhibitor, could indirectly impact CFAP61 by influencing ciliogenesis and related signaling processes. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Proteasome inhibitors like Bortezomib may affect CFAP61 indirectly by influencing protein turnover, potentially impacting cilia and flagella-associated proteins. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $36.00 $117.00 $525.00 | 26 | |
XAV-939, a Wnt/β-catenin pathway inhibitor, might have indirect effects on CFAP61 by influencing cilia-related signaling pathways. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride, known for inhibiting GSK-3β, may indirectly impact CFAP61 through pathways related to ciliogenesis and cellular signaling. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $40.00 $120.00 $480.00 $2141.00 | 47 | |
Notch pathway inhibitors like DAPT could indirectly affect CFAP61 by altering cellular differentiation processes that involve cilia. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
TGF-β pathway inhibitors such as SB-431542 might influence CFAP61 indirectly by modulating cellular signaling and differentiation related to cilia. | ||||||