C20orf194 Activators
Activators of C20orf194 can be understood as compounds that influence cellular pathways or processes which, in turn, may have an indirect effect on the expression or function of the protein. While direct activators are yet to be identified, the investigation into indirect activators involves delving into the myriad pathways that intersect with C20orf194's biological role. Cellular signaling, gene expression, and metabolic regulation represent the crucial arenas where indirect activators operate. For instance, compounds such as Dibutyryl-cAMP and Sildenafil can raise the levels of cyclic nucleotides, which are secondary messengers in a plethora of cellular processes, impacting the signaling landscape that C20orf194 is part of. Similarly, metabolic modulators like Pioglitazone and Beta-hydroxybutyrate offer pathways to indirectly influence C20orf194 through the alteration of lipid metabolism and energy balance, respectively.
The modulation of gene expression through epigenetic mechanisms, as seen with compounds like 5-Azacytidine, presents another route through which C20orf194 activity can be indirectly affected. These compounds do not act on C20orf194 directly but may modify the transcriptional milieu that governs its expression. Furthermore, compounds like Epigallocatechin gallate and Nicotinamide mononucleotide are involved in a broad spectrum of signaling and metabolic pathways, including the modulation of transcription factors and the cellular redox state. The perturbation of these complex networks through the aforementioned compounds can create an intracellular environment conducive to either the upregulation of C20orf194 expression or the enhancement of its protein stability and function. This intricate web of interactions underlines the indirect activators to modulate C20orf194 activity, providing a foundation for further exploration into the functional dynamics of this protein.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Dibutyryl-cAMP serves as a cAMP analog that can activate PKA. PKA then phosphorylates target proteins, which can lead to changes in gene expression and cellular processes that may enhance the activity or expression of C20orf194. | ||||||
Zoledronic acid, anhydrous | 118072-93-8 | sc-364663 sc-364663A | 25 mg 100 mg | $90.00 $251.00 | 5 | |
A bisphosphonate that inhibits farnesyl pyrophosphate synthase, leading to the accumulation of isopentenyl pyrophosphate, a molecule that may enhance the prenylation and thus the function of C20orf194 if it is prenylated. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
A PPARγ agonist that can alter lipid metabolism and adipogenesis, pathways that could indirectly influence the expression or function of C20orf194 by modulating the lipid environment of its activity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
An inhibitor of DNA methyltransferases, which can lead to demethylation of gene promoters, potentially increasing the transcription of C20orf194 if its promoter is subject to methylation control. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A polyphenol that can modulate multiple signaling pathways, potentially affecting gene expression profiles, including those of C20orf194, by altering transcription factor activity. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $92.00 $269.00 $337.00 $510.00 $969.00 | 4 | |
A precursor of NAD+ that can boost sirtuin activity and influence the cellular redox state, possibly affecting the expression or stabilization of C20orf194 through these pathways. | ||||||
3-Hydroxybutyric acid | 300-85-6 | sc-231749 sc-231749A sc-231749B | 1 g 5 g 25 g | $70.00 $120.00 $440.00 | ||
A ketone body that can act as a signaling metabolite, potentially affecting gene expression and protein function in a way that may indirectly increase the activity of C20orf194. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $33.00 $77.00 $175.00 | 3 | |
Involved in fatty acid transport into mitochondria, which could influence cellular energy metabolism in a manner that indirectly supports C20orf194 function, assuming it's linked to energy-dependent processes. | ||||||
3,4-Dihydroxyphenyl Ethanol | 10597-60-1 | sc-202887 | 10 mg | $110.00 | 6 | |
An antioxidant that can affect signaling pathways related to oxidative stress, potentially modifying the cellular environment in a way that supports C20orf194 activity or expression. | ||||||
Allicin | 539-86-6 | sc-202449 sc-202449A | 1 mg 5 mg | $460.00 $1428.00 | 7 | |
A compound in garlic that can affect sulfhydryl-containing proteins, potentially altering the redox state and influencing signaling pathways that may indirectly upregulate C20orf194. | ||||||