C20orf151 Inhibitors
C20orf151 Inhibitors are chemical compounds that can lead to the decreased functional activity of the protein C20orf151. The first six inhibitors – U0126, LY294002, SB203580, Wortmannin, SP600125, and Rapamycin – inhibit upstream components of various pathways including the MAPK/ERK, PI3K/AKT, and p38 MAPK pathways. This leads to a decrease in C20orf151 functionality if it is an effector in these pathways. For instance, U0126 and LY294002 inhibit MEK1/2 and PI3K respectively, preventing the downstream signaling events that may involve C20orf151.
The remaining six inhibitors – PD98059, Akti-1/2, AZD8055, PF-04691502, GSK690693, and FR180204 – also act on components of these pathways, but their targets are slightly different. For example, PD98059 and Akti-1/2 inhibit MEK and AKT respectively, while AZD8055 and PF-04691502 inhibit mTOR. GSK690693 is another AKT inhibitor, and FR180204 inhibits ERK. By inhibiting these molecules, these compounds can prevent downstream signaling events involving C20orf151, leading to a decrease in the protein's functional activity. For instance, AZD8055 and PF-04691502 can prevent downstream signaling in the PI3K/AKT/mTOR pathway, reducing the functional activity of C20orf151 if the protein is part of this pathway. Similarly, by inhibiting ERK, FR180204 suppresses downstream signaling in the MAPK/ERK pathway, potentially reducing the functional activity of C20orf151 if it is involved in this pathway.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor. It can inhibit the PI3K/AKT pathway and prevent the downstream signaling that may influence C20orf151 if it is part of this pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits p38 MAPK. If C20orf151 is involved in the p38 MAPK pathway, the protein's functional activity can be reduced due to the suppression of downstream signaling. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is another potent PI3K inhibitor. By inhibiting PI3K, it reduces downstream signaling and functional activity of C20orf151 if the protein is part of this pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a selective JNK inhibitor. By inhibiting JNK, it prevents downstream signaling events in the JNK/MAPK pathway, possibly leading to reduced functional activity of C20orf151 if the protein is involved in this pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor. It can prevent downstream signaling in the PI3K/AKT/mTOR pathway, reducing the functional activity of C20orf151 if the protein is part of this pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a MEK inhibitor. By inhibiting MEK, it suppresses the MAPK/ERK pathway and reduces the functional activity of C20orf151 if the protein is involved in this pathway. | ||||||
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 | 612847-09-3 | sc-202048 sc-202048A | 1 mg 5 mg | $208.00 $270.00 | 29 | |
Akti-1/2 is an AKT1/2 inhibitor. By inhibiting AKT1/2, it can reduce downstream signaling in the PI3K/AKT pathway, possibly leading to reduced functional activity of C20orf151 if the protein is involved in this pathway. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $163.00 $352.00 | 12 | |
AZD8055 is an mTOR inhibitor. It can prevent downstream signaling in the PI3K/AKT/mTOR pathway and reduce the functional activity of C20orf151 if the protein is part of this pathway. | ||||||
GSK 690693 | 937174-76-0 | sc-363280 sc-363280A | 10 mg 50 mg | $255.00 $1071.00 | 4 | |
GSK690693 is an AKT inhibitor. By inhibiting AKT, it suppresses downstream signaling in the PI3K/AKT pathway, possibly reducing the functional activity of C20orf151 if the protein is involved in this pathway. | ||||||
ERK Inhibitor II, FR180204 | 865362-74-9 | sc-203945 sc-203945A sc-203945B sc-203945C | 1 mg 5 mg 10 mg 50 mg | $110.00 $165.00 $239.00 $942.00 | 45 | |
FR180204 is an ERK inhibitor. By inhibiting ERK, it suppresses downstream signaling in the MAPK/ERK pathway, possibly reducing the functional activity of C20orf151 if the protein is involved in this pathway. | ||||||