C19orf12 inhibitors constitute a class of chemical compounds specifically designed to target and modulate the activity of the C19orf12 protein, also known as chromosome 19 open reading frame 12. C19orf12 is a relatively newly discovered protein with emerging relevance in cellular biology, particularly in mitochondrial and lipid metabolism. Although much remains to be elucidated about its precise functions, C19orf12 is thought to play a role in regulating mitochondrial morphology and function, as well as lipid metabolism. Inhibitors designed to target C19orf12 are primarily employed in molecular and cellular biology research to investigate the functional properties and regulatory mechanisms associated with this protein.
The development of C19orf12 inhibitors typically involves a combination of biochemical, biophysical, and structural approaches aimed at identifying or designing molecules that can selectively interact with C19orf12 and modulate its activity. By inhibiting C19orf12, these compounds can potentially interfere with its roles in mitochondrial dynamics and lipid metabolism, affecting cellular processes associated with energy production and lipid homeostasis. Researchers use C19orf12 inhibitors to explore the intricate roles played by this protein in various cellular contexts, unraveling its contributions to mitochondrial function, cellular energetics, and lipid-related processes. Furthermore, these inhibitors serve as valuable tools for dissecting the broader network of cellular pathways involving C19orf12, contributing to our understanding of fundamental cell biology mechanisms and providing insights into potential avenues for further scientific exploration.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Thenoyltrifluoroacetone | 326-91-0 | sc-251801 | 5 g | $37.00 | 1 | |
This compound is a chelating agent that may disrupt metal ion homeostasis in mitochondria, potentially affecting the expression of mitochondrial-associated proteins like C19orf12. | ||||||
Oligomycin A | 579-13-5 | sc-201551 sc-201551A sc-201551B sc-201551C sc-201551D | 5 mg 25 mg 100 mg 500 mg 1 g | $179.00 $612.00 $1203.00 $5202.00 $9364.00 | 26 | |
Oligomycin inhibits ATP synthase in mitochondria, potentially affecting mitochondrial function and indirectly impacting the expression of mitochondrial-related proteins such as C19orf12. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
Rotenone is an inhibitor of mitochondrial complex I, which could lead to altered mitochondrial function and potentially reduce the expression of C19orf12. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
As an inhibitor of mitochondrial complex III, antimycin A could disrupt normal mitochondrial function and thus indirectly affect the expression of C19orf12. | ||||||
Methylene blue | 61-73-4 | sc-215381B sc-215381 sc-215381A | 25 g 100 g 500 g | $43.00 $104.00 $328.00 | 3 | |
Methylene blue affects mitochondrial function and could potentially impact the expression of mitochondrial proteins, possibly including C19orf12. | ||||||
Tetracycline | 60-54-8 | sc-205858 sc-205858A sc-205858B sc-205858C sc-205858D | 10 g 25 g 100 g 500 g 1 kg | $63.00 $94.00 $270.00 $417.00 $634.00 | 6 | |
Tetracycline can influence mitochondrial protein synthesis due to its antibiotic properties, which might lead to an indirect reduction in C19orf12 expression. | ||||||
Doxycycline-d6 | 564-25-0 unlabeled | sc-218274 | 1 mg | $16500.00 | ||
Doxycycline might affect mitochondrial protein synthesis and thereby potentially decrease the expression of C19orf12. | ||||||
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $90.00 | 10 | |
Chloramphenicol inhibits bacterial protein synthesis and similarly may affect mitochondrial protein synthesis, potentially impacting C19orf12 expression. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $41.00 | 9 | |
Fenofibrate activates PPARα and alters the expression of genes involved in lipid metabolism, which could indirectly affect the expression of C19orf12. | ||||||
WY 14643 | 50892-23-4 | sc-203314 | 50 mg | $136.00 | 7 | |
This PPARα agonist affects lipid metabolism and may indirectly modulate the expression of genes like C19orf12 which are associated with lipid metabolic processes. | ||||||