C16orf48_E130303B06Rik Inhibitors
PI3K, JNK, p38 MAPK, and MEK, thereby affecting phosphorylation events that can regulate protein activity, localization, and protein-protein interactions. Inhibitors like Staurosporine, LY294002, SP600125, SB203580, U0126, and PD98059 fall into this category, each with the capacity to disrupt specific kinase signaling cascades that may be crucial for the function of C16orf48_E130303B06Rik.
Further more these chemicals that intervene in protein synthesis and degradation pathways, such as Rapamycin and MG132. Rapamycin's inhibition of mTOR can affect the translation of proteins, influencing cellular growth and metabolism, while MG132's proteasome inhibition can lead to the accumulation of proteins, impacting protein turnover and signaling. Cyclopamine's inhibition of the Hedgehog pathway and ZM-447439's disruption of Aurora kinase activity exemplify inhibitors that can affect developmental pathways and cell division, respectively, which are essential processes in cellular function and homeostasis. Gefitinib's role in EGFR inhibition can impact cell proliferation and apoptosis, while Y-27632 can affect cell structure and motility through its action on the ROCK pathway.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A non-selective protein kinase inhibitor that can interrupt signal transduction pathways regulated by phosphorylation, affecting protein activity and localization. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that can alter signaling pathways involved in cell survival, proliferation, and metabolism, thereby influencing protein function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor that can modify the JNK signaling pathway, thereby influencing activities of proteins regulated by this pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor that can alter the p38 signaling pathway, impacting the function of proteins that are regulated by p38 MAPK. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
A MEK inhibitor that can prevent the activation of ERK, thereby affecting proteins involved in the MAPK/ERK pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can alter protein synthesis pathways and thereby affect the function of proteins involved in such processes. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor that can stabilize proteins and impact the degradation of regulatory proteins, potentially affecting protein activity. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
A Hedgehog signaling pathway inhibitor that can impact the function of proteins regulated by this pathway. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
An Aurora kinase inhibitor that can disrupt mitotic processes, potentially impacting the function of proteins involved in cell cycle regulation. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $63.00 $114.00 $218.00 $349.00 | 74 | |
An EGFR inhibitor that can affect the EGFR signaling pathway, thereby impacting proteins that interact with this pathway. | ||||||