C16orf13_0610011F06Rik Inhibitors
Kinase inhibitors such as Staurosporine, which is known for its broad-spectrum kinase inhibitory activity and can alter the phosphorylation state of numerous proteins. Similarly, LY294002 and U0126 are specific inhibitors of PI3K and MEK1/2, respectively, and by inhibiting these kinases, they can modulate downstream signaling involving the Akt and ERK pathways, which are vital for numerous cellular processes, including those related to protein function and expression.
Other inhibitors like Rapamycin and Bortezomib work by inhibiting mTOR and the proteasome, respectively. Rapamycin's inhibition of mTOR can result in decreased protein synthesis, while Bortezomib can lead to an accumulation of proteins due to decreased degradation. Cyclopamine's role in inhibiting the Hedgehog pathway can affect cell differentiation and proliferation, while PD0325901, similar to U0126, can specifically inhibit MEK and influence the ERK pathway's activity. Chemicals such as SP600125 and ZM-447439 are involved in inhibiting the JNK pathway and Aurora kinases, respectively, potentially affecting various aspects of cell signaling and division. CNQX, by modulating synaptic transmission, can influence neuronal signaling pathways.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A potent kinase inhibitor that can inhibit a wide range of protein kinases, potentially affecting the phosphorylation state of the protein. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A phosphatidylinositol 3-kinase (PI3K) inhibitor, which can alter PI3K/Akt signaling and indirectly affect proteins regulated by this pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAP kinase inhibitor that can modulate the MAPK signaling pathway and influence protein functions regulated by this pathway. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
An inhibitor of MEK1/2, which can affect the ERK pathway and potentially alter the function of proteins controlled by this route. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can block the mTOR signaling pathway, influencing protein synthesis and function. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
A glucose transporter 1 (GLUT1) inhibitor, which can reduce glucose uptake and alter cellular metabolism, potentially affecting protein expression. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
A proteasome inhibitor that can increase protein levels by preventing their degradation, potentially affecting protein function. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
An inhibitor of the Hedgehog signaling pathway which can change the expression and function of proteins involved in this pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of the JNK signaling pathway which can alter the activity of proteins that are regulated by this pathway. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
An Aurora kinase inhibitor, which can affect cell cycle progression and the function of proteins involved in this process. | ||||||