C14orf159 Inhibitors
C14orf159 inhibitors are chemical compounds that limit the functional activity of the C14orf159 protein by disrupting specific signaling pathways or biological processes in which it is directly involved. For instance, Staurosporine and Genistein are potent inhibitors of protein kinases, including PKC and tyrosine kinases respectively, that are key regulators of cell proliferation and survival. By inhibiting these kinases, these compounds can interrupt corresponding signaling pathways and reduce the functional activity of C14orf159. Similarly, Wortmannin and LY294002 are potent inhibitors of PI3K, a kinase involved in many cellular functions including cell growth and proliferation. By inhibiting PI3K, these compounds can disrupt these processes, leading to decreased functional activity of C14orf159.
Several inhibitors, such as PD98059, U0126, and SB203580, target the MAPK/ERK pathway, which is also involved in cell proliferation and survival. Inhibition of this pathway by these compounds can decrease the functional activity of C14orf159. SP600125 and Y-27632 are selective inhibitors of JNK and ROCK respectively. JNK is a key regulator of apoptosis, and ROCK is involved in cell motility. Inhibition of these kinases can lead to decreased functional activity of C14orf159. Rapamycin is an mTOR inhibitor, which is involved in protein synthesis and cell growth. PD173074 is a potent inhibitor of FGFR tyrosine kinase, involved in cell growth and differentiation.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine inhibits protein kinases, such as PKC, which plays a key role in the regulation of cell proliferation and survival. C14orf159 is involved in these pathways, and by inhibiting PKC, Staurosporine reduces the functional activity of C14orf159. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is an irreversible inhibitor of PI3K. By inhibiting PI3K, Wortmannin disrupts cell growth and proliferation processes, which subsequently leads to decreased functional activity of C14orf159. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 inhibits MEK, a component of the MAPK/ERK pathway. By inhibiting this pathway, PD98059 can reduce the functional activity of C14orf159 which is involved in the ERK signaling pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits JNK, a regulator of apoptosis. By inhibiting JNK, SP600125 can decrease the functional activity of C14orf159, which is involved in the JNK signaling pathway. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 inhibits ROCK, a kinase that regulates cell motility. By inhibiting ROCK, Y-27632 can reduce the functional activity of C14orf159 which is involved in the ROCK signaling pathway. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 inhibits PI3K, a kinase involved in cell survival and proliferation. By inhibiting PI3K, LY294002 can reduce the functional activity of C14orf159. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 specifically inhibits p38 MAPK, which is involved in inflammation and cell differentiation. By inhibiting p38 MAPK, SB203580 can reduce the functional activity of C14orf159. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein inhibits protein tyrosine kinases, which are involved in cell signaling. By inhibiting these kinases, Genistein can reduce the functional activity of C14orf159. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 inhibits Src family kinases which are involved in cellular processes like proliferation, differentiation, and survival. By inhibiting Src kinases, PP2 can decrease the functional activity of C14orf159. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, which is involved in protein synthesis and cell growth. By inhibiting mTOR, Rapamycin can reduce the functional activity of C14orf159. | ||||||