Date published: 2026-4-24

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c-Src Activators

c-Src Activators are a class of molecules that play a crucial role in cellular signal transduction pathways. These molecules are primarily involved in regulating cell growth, differentiation, and migration. At the core of c-Src Activators lies the c-Src protein, a proto-oncogene that belongs to the Src family of kinases. Src kinases are key players in various cellular processes, including cell adhesion, proliferation, and cytoskeletal organization. The activation of c-Src is pivotal for initiating a cascade of intracellular events. c-Src Activators work by promoting the phosphorylation of specific tyrosine residues on the c-Src protein. This phosphorylation event triggers conformational changes, leading to the activation of downstream signaling pathways. These pathways can include the MAPK/ERK pathway, which is involved in cell growth, and the PI3K/AKT pathway, which regulates cell survival. Moreover, c-Src Activators can impact cell motility by influencing actin cytoskeleton dynamics, facilitating cell migration and invasion processes. Understanding the mechanisms and molecular interactions of c-Src Activators is essential in elucidating their role in normal cellular physiology and in diseases such as cancer, where dysregulation of these pathways can have significant implications. In summary, c-Src Activators form a critical class of molecules involved in regulating cell signaling processes, particularly those related to growth, differentiation, and migration. Their ability to activate c-Src and modulate downstream pathways makes them essential players in cellular biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Angiotensin II, Human

4474-91-3sc-363643
sc-363643A
sc-363643B
sc-363643C
1 mg
5 mg
25 mg
100 mg
$51.00
$100.00
$310.00
$690.00
3
(1)

ngiotensin II, Human (CAS 4474-91-3), activates c-Src by binding to AT1R receptors, initiating intracellular signaling pathways. This activation influences cell proliferation, survival, and motility.

PP 1

172889-26-8sc-203212
sc-203212A
1 mg
5 mg
$86.00
$145.00
6
(1)

PP1 can activate c-Src at low concentrations by disrupting its autoinhibited conformation, leading to its activation.

SU6656

330161-87-0sc-203286
sc-203286A
1 mg
5 mg
$57.00
$133.00
27
(1)

SU6656 can activate c-Src at low concentrations by binding to its inactive form and promoting its activation.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin activates c-Src indirectly through the insulin receptor, leading to downstream activation of various signaling pathways that include c-Src.

Lysophosphatidic Acid

325465-93-8sc-201053
sc-201053A
5 mg
25 mg
$98.00
$341.00
50
(3)

LPA binds to its G-protein-coupled receptor, leading to activation of c-Src through downstream signaling.

D-erythro-Sphingosine-1-phosphate

26993-30-6sc-201383
sc-201383D
sc-201383A
sc-201383B
sc-201383C
1 mg
2 mg
5 mg
10 mg
25 mg
$165.00
$322.00
$570.00
$907.00
$1727.00
7
(1)

S1P activates c-Src through G-protein-coupled receptor mechanisms, similar to LPA.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA is a PKC activator that can also activate c-Src through downstream signaling pathways.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

U0126 can activate c-Src by relieving negative feedback mechanisms at specific concentrations, leading to its activation.

Okadaic Acid

78111-17-8sc-3513
sc-3513A
sc-3513B
25 µg
100 µg
1 mg
$291.00
$530.00
$1800.00
78
(4)

Okadaic Acid activates c-Src by inhibiting protein phosphatases that would otherwise dephosphorylate and inactivate c-Src.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol activates c-Src by binding to its kinase domain, leading to its activation.