Date published: 2025-10-15

1-800-457-3801

SCBT Portrait Logo
Seach Input

BTG1 Inhibitors

BTG1 inhibitors represent a class of chemical compounds that have garnered attention in the field of molecular biology and cell cycle regulation. These inhibitors are specifically designed to target and modulate the activity of BTG1, also known as B-cell translocation gene 1. BTG1 is a multifunctional protein that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. It is considered a tumor suppressor gene, as its expression is often downregulated in cancer cells, and it is associated with the regulation of cell cycle progression and the response to external signals.

BTG1 inhibitors exert their effects by interfering with the function or expression of BTG1, disrupting its role in cell cycle regulation and other cellular processes. This interference can lead to alterations in cell proliferation, differentiation, and apoptotic pathways, ultimately impacting cellular behaviors and responses. Researchers utilize BTG1 inhibitors as valuable tools to investigate the specific roles of BTG1 in different cellular contexts and to better understand the molecular mechanisms underlying cell cycle control and cellular differentiation. While the precise applications and broader implications of BTG1 inhibitors continue to be subjects of ongoing research, their utility in elucidating the intricate molecular mechanisms that govern cell fate decisions and cellular responses to external stimuli is of paramount importance in the field of molecular biology and cell biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Diethylstilbestrol

56-53-1sc-204720
sc-204720A
sc-204720B
sc-204720C
sc-204720D
1 g
5 g
25 g
50 g
100 g
$70.00
$281.00
$536.00
$1076.00
$2142.00
3
(1)

Diethylstilbestrol is a synthetic estrogen that can modulate estrogen receptor-mediated gene expression, potentially decreasing BTG1 levels.

Cadmium chloride, anhydrous

10108-64-2sc-252533
sc-252533A
sc-252533B
10 g
50 g
500 g
$55.00
$179.00
$345.00
1
(1)

Cadmium can disrupt cellular homeostasis and alter gene expression profiles, including downregulation of BTG1 expression.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Cycloheximide inhibits eukaryotic protein synthesis by interfering with the translocation step, decreasing overall protein levels including BTG1.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

Methotrexate is a dihydrofolate reductase inhibitor that affects nucleotide synthesis and can downregulate the expression of some genes.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D intercalates into DNA, inhibiting the transcription process and potentially decreasing BTG1 expression.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$32.00
$170.00
$385.00
63
(1)

Etoposide inhibits DNA topoisomerase II, leading to DNA damage and potential downregulation of BTG1 expression.

Cisplatin

15663-27-1sc-200896
sc-200896A
100 mg
500 mg
$76.00
$216.00
101
(4)

Cisplatin forms DNA adducts, causing DNA damage and potentially modulating the transcription of various genes including BTG1.

Hydroxyurea

127-07-1sc-29061
sc-29061A
5 g
25 g
$76.00
$255.00
18
(1)

Hydroxyurea inhibits ribonucleotide reductase, affecting DNA synthesis and potentially downregulating BTG1 expression.

Arsenic(III) oxide

1327-53-3sc-210837
sc-210837A
250 g
1 kg
$87.00
$224.00
(0)

Arsenic trioxide can lead to oxidative stress and modulate signal transduction pathways, potentially decreasing BTG1 expression.

Doxorubicin

23214-92-8sc-280681
sc-280681A
1 mg
5 mg
$173.00
$418.00
43
(3)

Doxorubicin intercalates into DNA and disrupts topoisomerase-II, which can lead to changes in gene expression, including BTG1.