Date published: 2025-10-11

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BLM Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of BLM Antibodies for research focused on understanding BLM protein functions. BLM Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). BLM protein, a member of the RecQ helicase family, plays a critical role in maintaining genomic stability by unwinding DNA during replication and repair processes. Mutations in the BLM gene are associated with Bloom syndrome, a disorder characterized by increased cancer susceptibility and other developmental issues. Understanding BLM protein function is essential for elucidating mechanisms of DNA repair and the prevention of genomic instability. Research utilizing BLM monoclonal antibodies has revealed significant insights into DNA repair pathways and their relationship to cancer development. Ongoing studies continue to uncover new aspects of BLM protein's role in maintaining chromosome stability and preventing premature aging. Recent findings have highlighted BLM protein's involvement in telomere maintenance and DNA crosslink repair. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance our understanding of genomic stability and its implications in human health and disease.

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BLM Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

BLM Antibody (B-4)

sc-365753mouse IgG2b κ1118-1417 (h)WB, IP, IF, ELISAm, r, h
16
(5)

BLM Antibody (BFL103)

sc-13584mouse IgG1 κFL (h)WB, IF, ELISAh
3
(3)

BLM Antibody (C-1)

sc-376237mouse IgG1 κ1393-1417 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(3)

BLM Antibody (F-5)

sc-376616mouse IgM κ1393-1417 (h)WB, IP, IF, ELISAh
1
(2)

BLM Antibody (4i317)

sc-70426mouse IgG1 κFL (h)WB, IFh
2
(1)

BLM CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BLM CRISPR/Cas9 KO Plasmid (h)

sc-400896hGene KnockoutGFP0
(0)

BLM HDR Plasmid (h)

sc-400896-HDRhHomology Directed RepairPuromycin0
(0)

BLM Double Nickase Plasmid (h)

sc-400896-NIChGene KnockoutPuromycin0
(0)

BLM Double Nickase Plasmid (h2)

sc-400896-NIC-2hGene KnockoutPuromycin0
(0)

BLM CRISPR/Cas9 KO Plasmid (m)

sc-419336mGene KnockoutGFP0
(0)

BLM HDR Plasmid (m2)

sc-419336-HDR-2mHomology Directed RepairPuromycin0
(0)

BLM Double Nickase Plasmid (m)

sc-419336-NICmGene KnockoutPuromycin0
(0)

BLM Double Nickase Plasmid (m2)

sc-419336-NIC-2mGene KnockoutPuromycin0
(0)

BLM CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BLM CRISPR Activation Plasmid (h)

sc-400896-ACThGene ActivationPuro, Blast, Hygro0
(0)

BLM CRISPR Activation Plasmid (h2)

sc-400896-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

BLM Lentiviral Activation Particles (h)

sc-400896-LAChGene ActivationPuro, Blast, Hygro0
(0)

BLM Lentiviral Activation Particles (h2)

sc-400896-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

BLM CRISPR Activation Plasmid (m)

sc-419336-ACTmGene ActivationPuro, Blast, Hygro0
(0)

BLM CRISPR Activation Plasmid (m2)

sc-419336-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

BLM Lentiviral Activation Particles (m)

sc-419336-LACmGene ActivationPuro, Blast, Hygro0
(0)

BLM Lentiviral Activation Particles (m2)

sc-419336-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

BLM siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BLM siRNA (h)

sc-29808hGene SilencingN/A
1
(0)

BLM shRNA Plasmid (h)

sc-29808-SHhGene SilencingPuromycin
1
(0)

BLM shRNA (h) Lentiviral Particles

sc-29808-VhGene SilencingPuromycin
1
(0)

BLM siRNA (m)

sc-29809mGene SilencingN/A
1
(0)

BLM shRNA Plasmid (m)

sc-29809-SHmGene SilencingPuromycin
1
(0)

BLM shRNA (m) Lentiviral Particles

sc-29809-VmGene SilencingPuromycin
1
(0)