Bles03 inhibitors presented here encompass compounds that primarily operate on wide-ranging cellular mechanisms and pathways, indirectly affecting the potential function or expression of Bles03. Proteasome inhibitors, such as Epoxomicin, MG132, and Bortezomib, are included for their potential to influence protein degradation, potentially modulating the stability or turnover of Bles03. On the transcription and translation front, Cycloheximide and Rapamycin have been highlighted for their respective roles in protein synthesis and the mTOR pathway.
Another significant realm explored is epigenetic modifications. Decitabine, which impacts DNA methylation, and Mocetinostat, a histone deacetylase inhibitor, could play a role in modulating Bles03 gene expression. JQ1's inclusion stems from its bromodomain inhibition, potentially affecting transcription factors linked to Bles03. Lastly, the potential relationship of Bles03 to broader cellular processes like DNA repair and apoptosis has led to the inclusion of Olaparib, a PARP inhibitor, and Z-VAD-FMK, a caspase inhibitor. Their roles could be pivotal if Bles03 has any association with these processes.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $67.00 $306.00 | 2 | |
Can inhibit several kinases; could potentially alter phosphorylation status or pathways related to Bles03. | ||||||
Epoxomicin | 134381-21-8 | sc-201298C sc-201298 sc-201298A sc-201298B | 50 µg 100 µg 250 µg 500 µg | $134.00 $215.00 $440.00 $496.00 | 19 | |
A proteasome inhibitor; could potentially affect degradation processes linked to Bles03. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor; might influence protein stability or degradation processes of Bles03. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Another proteasome inhibitor; may affect turnover or stability of proteins like Bles03. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Can inhibit mTOR pathway, potentially influencing translation or other cellular processes related to Bles03. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits protein synthesis; could affect Bles03 production. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
Bromodomain inhibitor; can affect transcription factors and potentially modulate Bles03 gene expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Can alter DNA methylation patterns; could modulate Bles03 gene expression. | ||||||
Mocetinostat | 726169-73-9 | sc-364539 sc-364539B sc-364539A | 5 mg 10 mg 50 mg | $210.00 $242.00 $1434.00 | 2 | |
Histone deacetylase inhibitor; could affect chromatin structure and Bles03 transcription. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
p53 pathway activator; if Bles03 is in any way linked to p53 pathway, this could influence its activity. |