BCLP Activators
BCLP Activators, also known as transmembrane protein 54 (TMEM54) activators, represent a specialized class of chemical compounds that have garnered attention within the realm of molecular biology and cellular processes. These compounds are meticulously designed to modulate the activity of BCLP, a protein-coding gene with diverse roles in various cellular functions. BCLP, or BCL2-Like Protein, shares structural similarities with BCL2 family members, known for their involvement in apoptosis regulation and the control of cellular survival. BCLP activators function by targeting specific regulatory elements within the BCLP gene, often located in promoter or enhancer regions, with the primary goal of enhancing its transcription and subsequent translation into functional protein products.
The precise mechanisms through which BCLP activators exert their effects may vary, but their central objective is to act as molecular switches, amplifying the activity of BCLP. Researchers are continually exploring the potential applications and implications of BCLP activation, aiming to deepen our understanding of how this gene contributes to cellular processes, particularly within the context of apoptosis regulation and cellular survival pathways. This class of compounds holds promise for advancing our knowledge of gene regulation, specifically within the realm of BCL2-like proteins, offering insights into the intricate mechanisms that govern cell fate decisions and the significance of BCLP in various biological contexts. BCLP activators serve as valuable tools in the ongoing exploration of molecular biology, providing opportunities to uncover the complex roles that BCLP plays in cellular functions and its potential involvement in apoptosis and survival regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid regulates gene expression by acting as a ligand for retinoic acid receptors, which can modulate transcription of various genes. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3 (cholecalciferol) can be converted to its active form and bind to the vitamin D receptor, potentially influencing gene expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor and has been shown to modulate the activity of various transcription factors, potentially affecting gene expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
This compound is a DNA methyltransferase inhibitor that can cause DNA demethylation, potentially leading to gene reactivation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor, which can lead to a more open chromatin structure and potentially activate gene expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Beta-estradiol binds to estrogen receptors, which can then act as transcription factors to modulate the expression of certain genes. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate inhibits histone deacetylases, causing changes in chromatin structure that can influence gene expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a synthetic glucocorticoid that can bind to glucocorticoid receptors and affect the transcription of responsive genes. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $63.00 $173.00 | 7 | |
Cobalt(II) chloride can mimic hypoxia and induce hypoxia-inducible factors, which can alter the expression of various genes. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane can affect transcription factors like Nrf2, potentially influencing the expression of antioxidant response genes. | ||||||