BC056474 Activators
BC056474 Activators encompass a diverse set of chemical compounds that enhance the protein's activity through various biochemical mechanisms. Forskolin, by increasing intracellular cAMP levels, can activate protein kinase A (PKA), which may lead to the phosphorylation and activation of BC056474 or its interacting partners. Similarly, PMA acts as an activator of protein kinase C (PKC), potentially resulting in the phosphorylation of BC056474 and thereby enhancing its activity. Ionomycin, by increasing intracellular calcium levels, can activate calcium-dependent kinases that may phosphorylate BC056474, while sphingosine-1-phosphate may initiate signaling cascades via its receptors that ultimately lead to BC056474 activation. EGCG, by inhibiting specific kinases, can relieve inhibitory phosphorylation on BC056474 or its pathway components, thereby increasing its activity. LY294002, through PI3K pathway modulation, and U0126, by inhibiting the MEK1/2 ERK pathway, could both alter the phosphorylation landscape in a way that favors BC056474 activation.
Continuing the exploration of BC056474 activators,BC056474 Activators comprise a specific set of chemical compounds that indirectly augment the functional activity of BC056474 by modulating various signaling pathways and biological processes. Forskolin, by elevating intracellular cAMP levels, can lead to the activation of protein kinase A (PKA), which may then phosphorylate substrates that are part of BC056474's signaling network, enhancing its activity. Phorbol 12-myristate 13-acetate (PMA) serves as an activator of protein kinase C (PKC), which could phosphorylate and activate BC056474 or associated proteins within its pathway. Ionomycin, as a calcium ionophore, increases intracellular calcium levels, potentially triggering calcium-dependent protein kinases that could lead to the activation of BC056474. Additionally, sphingosine-1-phosphate, operating through its receptors, might initiate signaling events that culminate in the enhancement of BC056474's activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC), which can phosphorylate a variety of substrates, potentially including BC056474, resulting in its enhanced activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium concentration, potentially activating calcium-dependent kinases that could phosphorylate and activate BC056474. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
Sphingosine-1-phosphate activates sphingosine-1-phosphate receptors, which could lead to downstream signaling enhancing the activity of BC056474 through kinase activation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG inhibits certain kinases, which may reduce negative regulatory phosphorylation on BC056474 or its pathway components, indirectly enhancing BC056474 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that could indirectly enhance BC056474 activity by modulating the PI3K/AKT pathway, leading to altered phosphorylation states of BC056474 or associated proteins. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 inhibits MEK1/2, which may shift signaling dynamics in favor of pathways that activate BC056474, if BC056474 is negatively regulated by ERK signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor that might enhance BC056474 activity by inhibiting p38-dependent phosphorylation that negatively regulates BC056474's function. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine, a broad-spectrum kinase inhibitor, could selectively enhance BC056474 activity by inhibiting kinases that negatively regulate BC056474. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin disrupts calcium homeostasis by blocking the ER calcium ATPase, potentially leading to the activation of calcium-dependent proteins that could enhance BC056474 activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor that could potentiate BC056474 activity by reducing competitive tyrosine kinase signaling, thereby indirectly enhancing signaling pathways involving BC056474. | ||||||