BC002199 Activators
BC002199 activators comprise a collection of chemical compounds that influence various biochemical signaling pathways to indirectly enhance the activity of BC002199. Compounds like Cyclic AMP and Forskolin facilitate an increase in intracellular cAMP levels, which can stimulate protein kinase A (PKA) to phosphorylate target substrates that may include BC002199 or its associated proteins. This phosphorylation could lead to an enhancement of BC002199's activity within its respective signaling pathways. BC002199 Activators are a varied group of chemical compounds that enhance the activity of BC002199 through their influence on distinct signaling pathways and molecular mechanisms. Cyclic AMP and its stable analog 8-Br-cAMP, for example, act as second messengers to activate protein kinase A (PKA), potentially leading to the phosphorylation of BC002199, which would enhance its activity. Forskolin also raises cAMP levels, further supporting the activity of PKA in this cascade.
BC002199 Activators denotes a class of chemical compounds that are identified based on their capacity to activate the biological function associated with the molecule represented by the code BC002199. The discovery process for these activators begins with high-throughput screening (HTS), a technique that allows for the rapid evaluation of a vast library of chemicals to identify those that can enhance the activity of BC002199. HTS utilizes a variety of assays, often dependent on detecting a change in signal that corresponds to an increase in activity due to the presence of an activator. Such assays might measure changes in fluorescence, luminescence, or absorbance that indicate an interaction or an increase in biological activity of BC002199. Compounds that exhibit a significant increase in signal are singled out for further study.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
cAMP is a second messenger important in many biological processes. BC002199, being a hypothetical protein involved in signaling pathways, could be activated by cAMP through PKA activation, which may phosphorylate BC002199 or associated proteins, thus enhancing its functional activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a diacylglycerol analog that activates protein kinase C (PKC). PKC activation could lead to the phosphorylation of proteins in signaling pathways that include BC002199, enhancing its functional role. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore which increases intracellular calcium concentration. Elevated calcium levels can activate calmodulin-dependent kinases, potentially enhancing the activity of BC002199 if it is calcium-dependent. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin activates the PI3K/Akt signaling pathway, which could lead to the activation of downstream proteins that may include BC002199, assuming BC002199 plays a role in metabolic pathways influenced by insulin. | ||||||
NOC-18 | 146724-94-9 | sc-202247 sc-202247A sc-202247B sc-202247C | 10 mg 50 mg 100 mg 500 mg | $50.00 $180.00 $299.00 $1100.00 | 18 | |
Nitric oxide donors release NO, which can activate guanylate cyclase and increase cGMP levels. If BC002199 is involved in cGMP-dependent signaling, NO donors could enhance its activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium inhibits GSK-3, which may lead to the activation of Wnt signaling. If BC002199 is part of the Wnt signaling pathway, its activity could be indirectly enhanced by lithium chloride. | ||||||
8-Bromoadenosine 3′,5′-cyclic monophosphate | 23583-48-4 | sc-217493B sc-217493 sc-217493A sc-217493C sc-217493D | 25 mg 50 mg 100 mg 250 mg 500 mg | $106.00 $166.00 $289.00 $550.00 $819.00 | 2 | |
This cAMP analog is resistant to degradation by phosphodiesterases and could enhance BC002199 activity by maintaining elevated cAMP levels, assuming BC002199 is in a cAMP-dependent pathway. | ||||||
Ouabain-d3 (Major) | sc-478417 | 1 mg | $506.00 | |||
Ouabain inhibits the Na+/K+-ATPase pump, potentially leading to increased intracellular calcium levels and subsequent activation of calcium-dependent pathways that could include BC002199. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $325.00 $632.00 $1428.00 $2450.00 $400.00 | 32 | |
Calcitriol, the active form of vitamin D, modulates gene expression through the vitamin D receptor. If BC002199 is regulated by gene transcription dependent on vitamin D signaling, its activity could be enhanced by calcitriol. | ||||||