Date published: 2026-6-25

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Barhl1 Inhibitors

Barhl1 Inhibitors represent a class of chemical compounds designed to modulate the activity of the Barhl1 protein, which is a transcription factor involved in the regulation of gene expression during embryonic development, particularly in neural differentiation processes. These inhibitors are developed to specifically target the Barhl1 protein and interfere with its transcriptional activity. The objective of such inhibitors is to gain insights into the molecular mechanisms through which Barhl1 functions and to explore its roles in various developmental processes.

The development of Barhl1 inhibitors is rooted in the broader field of molecular biology and developmental biology, aiming to understand the intricate regulatory networks that govern neural development. These inhibitors are designed to selectively bind to Barhl1 and alter its interaction with DNA or other proteins, thereby affecting the expression of downstream target genes. Researchers utilize these inhibitors as tools for experimental purposes, dissecting the precise functions of Barhl1 in the context of embryogenesis and neural differentiation. By inhibiting Barhl1 activity, scientists can investigate the effects on neural cell fate determination and the molecular pathways influenced by this transcription factor, contributing to a deeper understanding of the complex processes that underlie embryonic development. It's important to note that Barhl1 inhibitors are primarily used as research reagents and are valuable for advancing our knowledge of gene regulation and neural development.

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Items 21 to 24 of 24 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Everolimus

159351-69-6sc-218452
sc-218452A
5 mg
50 mg
$131.00
$651.00
7
(1)

Inhibits mTOR, a serine/threonine kinase, in the therapy of various cancers and immune disorders.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

U0126 inhibits MEK1/2, preventing activation of the MAPK/ERK signaling pathway, which leads to down-regulation of Barhl1 expression through modulation of transcription factors.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

LY294002 inhibits PI3K, disrupting downstream Akt signaling and leading to inhibition of pathways involved in cell survival and proliferation, ultimately suppressing Barhl1 expression.

Olaparib

763113-22-0sc-302017
sc-302017A
sc-302017B
250 mg
500 mg
1 g
$210.00
$305.00
$495.00
10
(1)

Inhibits poly(ADP-ribose) polymerase (PARP) enzymes, used in BRCA-mutated ovarian and breast cancer.