Date published: 2025-12-7

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BACE2 Antibodies

Santa Cruz Biotechnology features a diverse variety of BACE2 monoclonal antibodies for research focused on understanding BACE2 protein function. BACE2 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).BACE2, or Beta-site APP Cleaving Enzyme 2, is a crucial enzyme involved in the processing of amyloid precursor protein (APP), which plays a significant role in Alzheimer's disease. By cleaving APP, BACE2 influences amyloid-beta peptide production, affecting neurodegenerative processes. Understanding BACE2 function is essential for developing therapeutic strategies aimed at mitigating the effects of Alzheimer's disease and other related disorders. Research utilizing BACE2 monoclonal antibodies has revealed important insights into APP processing pathways and potential therapeutic targets. Investigating BACE2 expression patterns helps identify its role in different tissues and cellular compartments. Studying BACE2 activity provides valuable information about its regulation and potential intervention points. Santa Cruz Biotechnology monoclonal antibodies for BACE2 support researchers worldwide in advancing our understanding of neurodegenerative diseases and developing new therapeutic approaches.

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BACE2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

BACE2 Antibody (H-3)

sc-271212mouse IgG2b κ429-518 (h)WB, IP, IF, IHC(P), ELISAm, r, h
7
(4)

BACE2 Antibody (F-12)

sc-271286mouse IgG1 κ429-518 (h)WB, IP, IF, ELISAm, r, h
1
(1)

BACE2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BACE2 CRISPR/Cas9 KO Plasmid (h)

sc-403147hGene KnockoutGFP0
(0)

BACE2 HDR Plasmid (h)

sc-403147-HDRhHomology Directed RepairPuromycin0
(0)

BACE2 Double Nickase Plasmid (h)

sc-403147-NIChGene KnockoutPuromycin0
(0)

BACE2 Double Nickase Plasmid (h2)

sc-403147-NIC-2hGene KnockoutPuromycin0
(0)

BACE2 CRISPR/Cas9 KO Plasmid (m)

sc-425013mGene KnockoutGFP0
(0)

BACE2 HDR Plasmid (m)

sc-425013-HDRmHomology Directed RepairPuromycin0
(0)

BACE2 Double Nickase Plasmid (m)

sc-425013-NICmGene KnockoutPuromycin0
(0)

BACE2 Double Nickase Plasmid (m2)

sc-425013-NIC-2mGene KnockoutPuromycin0
(0)

BACE2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BACE2 CRISPR Activation Plasmid (h)

sc-403147-ACThGene ActivationPuro, Blast, Hygro0
(0)

BACE2 CRISPR Activation Plasmid (h2)

sc-403147-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

BACE2 Lentiviral Activation Particles (h)

sc-403147-LAChGene ActivationPuro, Blast, Hygro0
(0)

BACE2 Lentiviral Activation Particles (h2)

sc-403147-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

BACE2 CRISPR Activation Plasmid (m)

sc-425013-ACTmGene ActivationPuro, Blast, Hygro0
(0)

BACE2 CRISPR Activation Plasmid (m2)

sc-425013-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

BACE2 Lentiviral Activation Particles (m)

sc-425013-LACmGene ActivationPuro, Blast, Hygro0
(0)

BACE2 Lentiviral Activation Particles (m2)

sc-425013-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

BACE2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BACE2 siRNA (h)

sc-29776hGene SilencingN/A
2
(0)

BACE2 shRNA Plasmid (h)

sc-29776-SHhGene SilencingPuromycin
2
(0)

BACE2 shRNA (h) Lentiviral Particles

sc-29776-VhGene SilencingPuromycin
2
(0)

BACE2 siRNA (m)

sc-29777mGene SilencingN/A
1
(0)

BACE2 shRNA Plasmid (m)

sc-29777-SHmGene SilencingPuromycin
1
(0)

BACE2 shRNA (m) Lentiviral Particles

sc-29777-VmGene SilencingPuromycin
1
(0)