ATAD4 Activators
In the context of ATAD4, these chemicals mainly function by modulating cellular energy levels, ATPase activity, and pathways that might involve ATAD4. For example, compounds like ATP and Pyruvate can directly influence ATP levels in the cell, giving ATAD4 more substrate to work on, thus increasing its activity. Similarly, chemicals like Dibutyryl-cAMP and Forskolin modulate the levels of cAMP, which indirectly affects a range of ATPase activities,including those of ATAD4.
Additionally, some of these compounds like Resveratrol and AICAR act on energy-sensing pathways, notably involving AMPK and Sirt1, which can indirectly influence cellular ATPase activities. These pathways often cross-talk with other pathways where ATPases play a key role, and by modulating these, one can hypothesize a ripple effect that may end up activating ATAD4. Given the role of ATPases in vesicle fusion and protein quality control, chemicals like Rho Kinase Inhibitor and Spermidine offer another layer of potential indirect activation by affecting these pathways.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ATP | 56-65-5 | sc-507511 | 5 g | $17.00 | ||
Elevates cellular ATP levels, potentially enhancing ATAD4's ATPase activity. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Activates Protein Kinase A (PKA) which can promote ATPase activity indirectly affecting ATAD4. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Stimulates adenylate cyclase, increasing cAMP levels, indirectly influencing ATPase activities. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Aids in mitochondrial ATP production which could increase ATAD4's substrate availability. | ||||||
Pyruvic acid | 127-17-3 | sc-208191 sc-208191A | 25 g 100 g | $40.00 $94.00 | ||
Fuels the Krebs cycle, increasing ATP production and potentially activating ATAD4's ATPase activity. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
Increases cellular stress leading to an upregulation of ATPase activities, potentially including ATAD4. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Activates Sirt1, indirectly influencing cellular energy homeostasis and thus possibly ATAD4 activity. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Impacts vesicle fusion pathways, possibly enhancing ATAD4's role in these processes. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
Activates AMPK, affecting cellular energy status and potentially indirectly activating ATAD4. | ||||||
Melatonin | 73-31-4 | sc-207848 sc-207848A sc-207848B sc-207848C sc-207848D sc-207848E | 1 g 5 g 25 g 100 g 250 g 1 kg | $64.00 $72.00 $214.00 $683.00 $1173.00 $3504.00 | 16 | |
Enhances mitochondrial function which can lead to higher ATP levels, affecting ATAD4 indirectly. | ||||||