ARMC4 inhibitors belong to a specific chemical class designed to target and modulate the activity of ARMC4, also known as Armadillo Repeat-Containing 4. ARMC4 is a protein encoded by the ARMC4 gene and plays a crucial role in cellular processes related to the cytoskeleton, cell adhesion, and signal transduction. The inhibition of ARMC4 is of particular interest due to its involvement in various cellular functions, making it a potential target for intervention. The chemical structures of ARMC4 inhibitors are meticulously designed to interact selectively with the active site of the ARMC4 protein, disrupting its normal function and affecting downstream signaling pathways.
ARMC4 inhibitors involves a deep understanding of the structural and biochemical aspects of the ARMC4 protein. Researchers employ rational drug design approaches and computational methods to identify and optimize compounds that exhibit high affinity and specificity for ARMC4. These inhibitors may function through various mechanisms, such as competitive binding to the active site or allosteric modulation, ultimately influencing the biological activities associated with ARMC4. The exploration of ARMC4 inhibitors contributes not only to advancing our understanding of cellular processes but also holds potential implications for future drug discovery efforts targeting diseases or conditions where ARMC4 dysregulation is a contributing factor.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Trichloroacetaldehyde-13C2 | sc-474862 | 2.5 mg | $380.00 | |||
Interferes with ciliary beating by disrupting dynein ATPase activity, possibly affecting ARMC4. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Binds to tubulin, potentially disrupting microtubule polymerization and cilia function. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Microtubule destabilizer that can indirectly affect ciliary structure, impacting ARMC4's role. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Inhibits actin polymerization, potentially affecting ciliary assembly linked with ARMC4. | ||||||
Aurintricarboxylic Acid | 4431-00-9 | sc-3525 sc-3525A sc-3525B sc-3525C | 100 mg 1 g 5 g 10 g | $20.00 $31.00 $47.00 $92.00 | 13 | |
Inhibits nucleases and may indirectly affect the cellular processes involving ARMC4. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Tyrosine kinase inhibitor that may indirectly influence ciliary function and ARMC4's role. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Disrupts microfilaments and could affect ciliary assembly involving ARMC4. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Binds tubulin, potentially affecting microtubule dynamics and indirectly ARMC4. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Stabilizes microtubules, possibly impacting cilia structure and ARMC4 function. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Interacts with microtubules and can disrupt mitotic spindles, potentially affecting ARMC4. |