ARGLU1 Activators
ARGLU1 Activators are a class of compounds that can enhance the function of the ARGLU1 protein through their influence on specific cellular pathways. These compounds can activate proteins in the sirtuin pathway, especially SIRT1, which is an NAD+-dependent deacetylase. Activation of SIRT1 leads to deacetylation and activation of FOXO transcription factors, which are known to regulate the transcription of ARGLU1. These compounds include both naturally occurring substances such as resveratrol, quercetin, berberine, honokiol, epicatechin, and capsaicin, and synthetic compounds like SRT1720, SRT2104, and CAY10602
Nicotinamide, a form of vitamin B3, also plays a role in enhancing ARGLU1 function, but it does so as a precursor to the coenzymes NAD+ and NADP+. These coenzymes are integral to the functioning of the sirtuin pathway, and by extension, the activation of ARGLU1. Therefore, the ARGLU1 Activators are a diverse group of compounds that operate through specific biochemical pathways to enhance the function of ARGLU1, either by acting on the sirtuin pathway, the AMPK pathway, or both. Through controlling the activity of these pathways, these compounds ensure an overall enhancement of ARGLU1 function.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
Nicotinamide is a form of vitamin B3 that serves as a precursor for the coenzymes NAD+ and NADP+, which are involved in multiple cellular redox reactions. ARGLU1 protein can be indirectly activated by this compound because it enhances the sirtuin pathway, where SIRT1, a NAD+-dependent deacetylase, can deacetylate and activate FOXO transcription factors, thus leading to enhanced transcription of ARGLU1. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a polyphenolic compound known to activate SIRT1, an NAD+-dependent deacetylase. This activation leads to the deacetylation and activation of FOXO transcription factors, enhancing the transcription of ARGLU1. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR is an analog of AMP that is capable of activating AMPK. Once AMPK is activated, it can lead to the activation of SIRT1, which then activates FOXO transcription factors, enhancing the transcription of ARGLU1. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid that can activate SIRT1. Through SIRT1 activation, FOXO transcription factors are activated and consequently enhance the transcription of ARGLU1. | ||||||
SRT1720 | 1001645-58-4 | sc-364624 sc-364624A | 5 mg 10 mg | $197.00 $364.00 | 13 | |
SRT1720 is a specific activator of SIRT1. Its activation of SIRT1 leads to the activation of FOXO transcription factors, which enhances the transcription of ARGLU1. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine is a natural isoquinoline alkaloid that can activate AMPK. AMPK activation leads to the activation of SIRT1, which in turn activates FOXO transcription factors, enhancing the transcription of ARGLU1. | ||||||
Honokiol | 35354-74-6 | sc-202653 sc-202653A | 10 mg 25 mg | $118.00 $178.00 | 4 | |
Honokiol is a lignan with multiple bioactive properties, including the activation of SIRT1. Through this activation, it leads to the deacetylation and activation of FOXO transcription factors, enhancing the transcription of ARGLU1. | ||||||
(−)Epicatechin | 490-46-0 | sc-205672 sc-205672A | 1 mg 5 mg | $51.00 $138.00 | ||
Epicatechin is a flavonoid that can activate SIRT1. Through this activation, it leads to the deacetylation and activation of FOXO transcription factors, enhancing the transcription of ARGLU1. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin is a natural alkaloid found in chili peppers. It can activate AMPK and thus lead to the activation of SIRT1, which in turn activates FOXO transcription factors, enhancing the transcription of ARGLU1. | ||||||