Date published: 2025-10-18

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AQP2 Antibodies

Santa Cruz Biotechnology offers a broad range of AQP2 monoclonal antibodies for investigating aquaporin-2 in various physiological processes. AQP2 monoclonal antibodies are compatible with multiple research applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Aquaporin-2 is a critical water channel protein primarily expressed in the kidney, where it plays a vital role in regulating water reabsorption and maintaining body fluid homeostasis. Dysregulation of aquaporin-2 can lead to various disorders, including nephrogenic diabetes insipidus and other renal pathologies. Understanding the function and regulation of aquaporin-2 is essential for developing therapeutic strategies for these conditions. Aquaporin-2 research has revealed significant insights into water transport mechanisms across cell membranes. Studying aquaporin-2 expression patterns helps identify potential therapeutic targets for treating water balance disorders. Advanced research techniques using aquaporin-2 detection methods continue to expand our understanding of kidney function and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies for AQP2 research enable scientists worldwide to advance our understanding of water regulation in health and disease.

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AQP2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Aquaporin 2/AQP2 Antibody (E-2)

sc-515770mouse IgG1 κ232-271 (h)WB, IP, IF, IHC(P), ELISAm, r, h
68
(6)

Aquaporin 2/AQP2 Antibody (G-3)

sc-515798mouse IgG2a κ232-271 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(0)

Aquaporin 2/AQP2 Antibody (E13-21)

sc-47710mouse IgM κC-Terminal (r)WB, IP, IFm, r, h
5
(6)

AQP2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Aquaporin 2/AQP2 CRISPR/Cas9 KO Plasmid (h)

sc-400402hGene KnockoutGFP0
(0)

Aquaporin 2/AQP2 CRISPR/Cas9 KO Plasmid (h2)

sc-400402-KO-2hGene KnockoutGFP0
(0)

Aquaporin 2/AQP2 HDR Plasmid (h2)

sc-400402-HDR-2hHomology Directed RepairPuromycin0
(0)

Aquaporin 2/AQP2 Double Nickase Plasmid (h)

sc-400402-NIChGene KnockoutPuromycin0
(0)

Aquaporin 2/AQP2 Double Nickase Plasmid (h2)

sc-400402-NIC-2hGene KnockoutPuromycin0
(0)

Aquaporin 2/AQP2 CRISPR/Cas9 KO Plasmid (m)

sc-419173mGene KnockoutGFP0
(0)

Aquaporin 2/AQP2 HDR Plasmid (m)

sc-419173-HDRmHomology Directed RepairPuromycin0
(0)

Aquaporin 2/AQP2 Double Nickase Plasmid (m)

sc-419173-NICmGene KnockoutPuromycin0
(0)

Aquaporin 2/AQP2 Double Nickase Plasmid (m2)

sc-419173-NIC-2mGene KnockoutPuromycin0
(0)

AQP2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Aquaporin 2/AQP2 CRISPR Activation Plasmid (h)

sc-400402-ACThGene ActivationPuro, Blast, Hygro0
(0)

Aquaporin 2/AQP2 CRISPR Activation Plasmid (h2)

sc-400402-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Aquaporin 2/AQP2 Lentiviral Activation Particles (h)

sc-400402-LAChGene ActivationPuro, Blast, Hygro0
(0)

Aquaporin 2/AQP2 Lentiviral Activation Particles (h2)

sc-400402-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Aquaporin 2/AQP2 CRISPR Activation Plasmid (m)

sc-419173-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Aquaporin 2/AQP2 CRISPR Activation Plasmid (m2)

sc-419173-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Aquaporin 2/AQP2 Lentiviral Activation Particles (m)

sc-419173-LACmGene ActivationPuro, Blast, Hygro0
(0)

Aquaporin 2/AQP2 Lentiviral Activation Particles (m2)

sc-419173-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

AQP2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Aquaporin 2/AQP2 siRNA (h)

sc-42363hGene SilencingN/A0
(0)

Aquaporin 2/AQP2 shRNA Plasmid (h)

sc-42363-SHhGene SilencingPuromycin0
(0)

Aquaporin 2/AQP2 shRNA (h) Lentiviral Particles

sc-42363-VhGene SilencingPuromycin0
(0)

Aquaporin 2/AQP2 siRNA (m)

sc-42364mGene SilencingN/A0
(0)

Aquaporin 2/AQP2 shRNA Plasmid (m)

sc-42364-SHmGene SilencingPuromycin0
(0)

Aquaporin 2/AQP2 shRNA (m) Lentiviral Particles

sc-42364-VmGene SilencingPuromycin0
(0)