AQP11 Activators
Aquaporin-11 activators encompass a diverse class of chemicals that can influence the function or expression of this protein indirectly. This can be achieved through various cellular mechanisms such as regulation of cAMP levels through chemicals like forskolin and IBMX.
Another factor is the removal of known inhibitors of aquaporins such as Erythrosin B and Mercuric chloride. The presence of substrates such as glycerol can also indirectly indicate the activity of AQP11. Additionally, various intracellular signaling molecules and hormones such as PMA, Wortmannin, EGF, TGF-β1, Dexamethasone, Insulin, and TNF-α can also potentially influence the expression or activity of AQP11. This can be through various mechanisms such as phosphorylation, gene expression modulation, or through the activation of different cellular pathways.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a plant-derived compound that increases intracellular cAMP, which can indirectly influence the function of AQP11. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a non-selective inhibitor of phosphodiesterases, preventing cAMP degradation and thus indirectly affecting AQP11 function. | ||||||
Erythrosin extra bluish | 16423-68-0 | sc-214973 sc-214973A sc-214973B sc-214973C sc-214973D sc-214973E | 10 g 50 g 100 g 1 kg 5 kg 10 kg | $27.00 $76.00 $120.00 $781.00 $3500.00 $6665.00 | 3 | |
Erythrosin extra bluish is a food dye that has been reported to inhibit AQP11, therefore its removal could indirectly activate AQP11. | ||||||
Glycerol | 56-81-5 | sc-29095A sc-29095 | 100 ml 1 L | $56.00 $153.00 | 12 | |
Glycerol is a substrate for AQP11, therefore its presence can indicate the activity of AQP11. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a known activator of protein kinase C (PKC), which can phosphorylate and regulate the activity of various proteins, potentially including AQP11. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent PI3K inhibitor, which can affect many cellular processes, potentially including the regulation of AQP11. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone is a glucocorticoid that can affect the expression of many genes, potentially including AQP11. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin, a major hormone, can affect many cellular processes, potentially influencing the expression or activity of AQP11. | ||||||