ANKRD55 Inhibitors
ANKRD55 inhibitors, as per the list, primarily act through the indirect modulation of different signaling pathways. This includes the inhibition of kinases like protein kinase A and PI3K, which are known to interact with ANKRD proteins. Inhibitors such as Staurosporine and H-89 dihydrochloride disrupt the PKA pathway interactions, thereby reducing ANKRD55 function. Similarly, LY294002 and Wortmannin inhibit PI3K, preventing AKT phosphorylation and affecting downstream targets within the PI3K/AKT pathway, where ANKRD55 plays a role. Rapamycin, another inhibitor, suppresses the mTOR pathway, affecting downstream targets including ANKRD55.
Other inhibitors function by modulating cellular excitability or protein trafficking. Quinidine, for instance, alters cellular excitability by inhibiting voltage-gated sodium channels, influencing ANKRD55's potential role in cellular response to stimuli. Brefeldin A, on the other hand, disrupts protein trafficking, which impacts ANKRD55's cellular localization and subsequent function. Certain inhibitors, such as Nifedipine and 2-APB, focus on the regulation of intracellular calcium concentrations, influencing ANKRD55's potential role in calcium-dependent cellular processes.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent pan-kinase inhibitor. It can indirectly inhibit ANKRD55 by targeting the PKA pathway, which is known to interact with ANKRD proteins, leading to decreased protein function. | ||||||
H-89 dihydrochloride | 130964-39-5 | sc-3537 sc-3537A | 1 mg 10 mg | $94.00 $186.00 | 71 | |
H-89 is a potent and selective inhibitor of protein kinase A (PKA), which indirectly affects ANKRD55 by disrupting its interactions with PKA associated proteins. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor which indirectly inhibits ANKRD55 by preventing AKT phosphorylation, affecting downstream targets of the PI3K/AKT pathway, which ANKRD55 is involved in. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor which indirectly inhibits ANKRD55 by suppressing the mTOR pathway, affecting downstream targets including ANKRD55. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a selective inhibitor of MEK, which indirectly inhibits ANKRD55 by reducing ERK pathway stimulation, a pathway that has been linked to ANKRD55. | ||||||
Quinidine | 56-54-2 | sc-212614 | 10 g | $104.00 | 3 | |
Quinidine is a potent inhibitor of voltage-gated sodium channels, which indirectly inhibits ANKRD55 by altering cellular excitability and influencing ANKRD55's potential role in cellular response to stimuli. | ||||||
Propranolol | 525-66-6 | sc-507425 | 100 mg | $180.00 | ||
Propranolol is a non-selective beta-blocker that indirectly influences ANKRD55 via its action on beta-adrenergic receptors and subsequent downstream effects on intracellular signaling pathways. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A is an inhibitor of protein trafficking, which can indirectly affect ANKRD55 by impacting its cellular localization and subsequent function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent and irreversible inhibitor of PI3K, which indirectly inhibits ANKRD55 by preventing AKT phosphorylation, a process that the PI3K/AKT pathway, in which ANKRD55 is involved, regulates. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
Nifedipine is a calcium channel blocker which indirectly inhibits ANKRD55 by modulating intracellular calcium concentrations, which can influence ANKRD55's potential role in calcium-dependent cellular processes. | ||||||