ANKRD33B inhibitors encompass a range of chemical compounds that indirectly participate in the attenuation of its activity by modulating various cellular signaling pathways and processes that ANKRD33B is potentially involved in. Inhibition of kinase activity by some chemicals may lead to altered phosphorylation states within the cell, thereby affecting the function of ANKRD33B if it is regulated by phosphorylation. Similarly, the inhibition of PI3K and mTOR could lead to a reduction in AKT signaling and cellular growth signals, respectively, which might affect the stability or expression of ANKRD33B. The intricate balance of cell signaling is further exemplified by the use of compounds which disrupt Hedgehog signaling, as well as those which are specific to the MEK/ERK pathway, altering the activity of ANKRD33B if it is linked to these pathways.
Moreover, compounds which target JNK and p38 MAPK are part of the cellular stress response and inflammatory signaling that could indirectly modify ANKRD33B's function if it is involved in these responses. The Wnt and Notch signaling pathways, which are crucial in cell fate determination, are also potential targets of inhibition, implicating ANKRD33B if it has roles within these pathways. On a structural level, inhibition of ROCK affects cytoskeleton dynamics and cell motility, which could inhibit ANKRD33B's activity.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that may indirectly inhibit ANKRD33B by altering phosphorylation states of proteins within signaling pathways that ANKRD33B is part of, potentially altering its function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that could reduce AKT signaling, which might affect proteins like ANKRD33B that are modulated by AKT activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that could disrupt cellular growth and survival signals, affecting the stability or expression of ANKRD33B. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
A Hedgehog signaling pathway inhibitor that may indirectly influence ANKRD33B activity if ANKRD33B is linked to this pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A MEK inhibitor that may reduce ERK pathway signaling, affecting downstream proteins including ANKRD33B if it is involved in this pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor that could influence ANKRD33B by altering stress response or apoptosis pathways if ANKRD33B is associated with these responses. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor that could impact inflammatory response or stress response signaling, affecting ANKRD33B if it plays a role in these processes. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $94.00 $286.00 | 27 | |
An inhibitor of Wnt production that could indirectly affect ANKRD33B function if ANKRD33B is involved in Wnt signaling pathways. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $99.00 $335.00 $836.00 $2099.00 | 47 | |
A gamma-secretase inhibitor that may affect Notch signaling, influencing ANKRD33B if there is an association between ANKRD33B and Notch pathway. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor that may affect cytoskeleton organization and cell motility pathways, impacting ANKRD33B if it is related to these cellular processes. |