ANKRD12 Activators
ANKRD12, also known as Ankyrin Repeat Domain 12, is a protein that plays a significant role in the regulation of transcription and possibly other cellular processes. The ANKRD12 gene encodes this protein, which is characterized by the presence of ankyrin repeats-a common protein-protein interaction motif consisting of tandemly repeated sequences that are known to mediate interactions with various other proteins.
The structure of ANKRD12 includes multiple ankyrin repeats, which allow it to serve as a scaffold or mediator in the assembly of protein complexes. ANKRD12 is involved in chromatin remodeling and has been found to interact with nuclear hormone receptors such as the androgen receptor, suggesting its role in the regulation of gene expression in a hormone-dependent manner. This interaction is thought to influence the transcriptional activities of these receptors, thereby impacting the expression of genes in processes like development, metabolism, and cellular differentiation.Furthermore, ANKRD12 has been implicated in the regulation of transcription elongation by RNA polymerase II. Through its interactions with other proteins in the transcription machinery, ANKRD12 can modulate the rate of transcription elongation, which is a critical step in the control of gene expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a potent activator of Protein Kinase C (PKC), which can influence transcription factors and processes ANKRD12 is involved in. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor can alter gene expression patterns, potentially influencing ANKRD12-mediated transcription. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
As a histone deacetylase inhibitor, it can modify chromatin structure and affect transcriptional activities related to ANKRD12. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Involved in gene expression regulation, it might interact with pathways where ANKRD12 has a role. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
By increasing cAMP levels, Forskolin can modulate various signaling pathways that might intersect with ANKRD12 functions. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An inhibitor of MEK, which is part of the MAPK pathway, can indirectly influence ANKRD12 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, potentially affecting pathways that intersect with ANKRD12's roles. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
As an mTOR inhibitor, it can affect transcriptional processes where ANKRD12 is involved. | ||||||