AMIGO1 Activators
AMIGO1 Activators are a class of chemical compounds that directly or indirectly enhance the functional activity of AMIGO1. AMIGO1, also known as Adhesion Molecule With Ig-Like Domain 1, is involved in various cellular processes such as cell adhesion, neurite outgrowth, and signal transduction. Compounds like retinoic acid and epidermal growth factor (EGF) can enhance the functional activity of AMIGO1 by promoting processes that require AMIGO1-mediated cell adhesion, such as cell growth, differentiation, and survival. Their action leads to an increaseddemand for AMIGO1 activity, thereby enhancing its functionality.
Another group of AMIGO1 activators includes compounds that influence intracellular signaling pathways. Chemicals such as forskolin, cyclic AMP (cAMP), 8-Bromo-cAMP, and N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate (db-cAMP) enhance the functional activity of AMIGO1 by promoting cellular processes that rely on cAMP. This group of compounds stimulates pathways that are central to cellular functions, including cell adhesion and neurite outgrowth, both of which require AMIGO1 activity. Similarly, compounds like phorbol 12-myristate 13-acetate (PMA), which activates protein kinase C (PKC), enhance AMIGO1 activity by stimulating AMIGO1-dependent adhesion and signaling pathways. Sodium butyrate, a histone deacetylase (HDAC) inhibitor, promotes acetylation of histones associated with the AMIGO1 gene, leading to its increased expression and thereby enhancing its function. Lastly, compounds like acetylcholine and dopamine, neurotransmitters involved in signal transmission, enhance the functional activity of AMIGO1 by promoting neurotransmission, a process that requires AMIGO1-mediated cell adhesion and signaling.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid is a metabolite of vitamin A (retinol) that mediates the functions of vitamin A required for growth and development. AMIGO1 is involved in cell adhesion processes, and retinoic acid can enhance the functional activity of AMIGO1 by upregulating cell adhesion molecules, thereby promoting cell-cell interactions. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a compound isolated from the roots of Coleus forskohlii. It activates adenylyl cyclase and increases intracellular levels of cAMP. This can enhance the functional activity of AMIGO1 by promoting cellular processes that rely on cAMP, including cell adhesion and neurite outgrowth. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate is a short-chain fatty acid that has been shown to influence gene expression through its histone deacetylase (HDAC) inhibitory activity. It can enhance AMIGO1 activity by promoting acetylation of histones associated with the AMIGO1 gene, leading to its increased expression. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
cAMP is a second messenger important in many biological processes. It can enhance the functional activity of AMIGO1 by promoting cellular processes that rely on cAMP, including cell adhesion and neurite outgrowth. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a compound that activates protein kinase C (PKC), which regulates signal transduction pathways implicated in cell growth and differentiation. PMA can enhance the functional activity of AMIGO1 by activating PKC, which can stimulate AMIGO1-dependent adhesion and signaling pathways. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
8-Bromo-cAMP is a cell-permeable cAMP analog. It can enhance the functional activity of AMIGO1 by promoting cellular processes that rely on cAMP, including cell adhesion and neurite outgrowth. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine is a type of neurotransmitter. It can enhance the functional activity of AMIGO1 by promoting neurotransmission, a process that requires AMIGO1-mediated cell adhesion and signaling. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
db-cAMP is a cell-permeable cAMP analog. It can enhance the functional activity of AMIGO1 by promoting cellular processes that rely on cAMP, including cell adhesion and neurite outgrowth. | ||||||