Date published: 2025-10-5

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ALAS Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of ALAS Antibodies for investigating aminolevulinate synthase (ALAS) in biological processes. ALAS Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Aminolevulinate synthase functions as a key enzyme in the heme biosynthesis pathway, catalyzing the first step in producing porphyrins, which are essential for hemoglobin and other heme-containing proteins. ALAS regulation maintains cellular heme levels, and disruption can result in various disorders, including porphyrias and anemia. Research focused on ALAS activity provides insights into the mechanisms underlying these conditions. Understanding ALAS function advances knowledge about heme-related disorders and supports the development of therapeutic approaches. Investigating ALAS expression patterns helps reveal its role in different tissues and cellular processes. ALAS research contributes to understanding metabolic pathways and their impact on human health. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of heme biosynthesis and related diseases.

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ALAS Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

ALAS-E Antibody (D-4)

sc-166739mouse IgG1 κ61-80 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(3)

ALAS-H Antibody (F-5)

sc-137093mouse IgG1 κ57-210 (m)WB, IP, IF, ELISAm, r, h
3
(3)

ALAS-H Antibody (C-6)

sc-137094mouse IgG1 κ57-210 (m)WB, IP, IF, IHC(P), ELISAm, r, h
1
(2)

ALAS-H Antibody (A-6)

sc-365153mouse IgG1 κ57-210 (h)WB, IP, IF, ELISAh
2
(2)

ALAS CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ALAS-E CRISPR/Cas9 KO Plasmid (h)

sc-403752hGene KnockoutGFP0
(0)

ALAS-E HDR Plasmid (h2)

sc-403752-HDR-2hHomology Directed RepairPuromycin0
(0)

ALAS-E Double Nickase Plasmid (h)

sc-403752-NIChGene KnockoutPuromycin0
(0)

ALAS-E Double Nickase Plasmid (h2)

sc-403752-NIC-2hGene KnockoutPuromycin0
(0)

ALAS-E CRISPR/Cas9 KO Plasmid (m)

sc-419074mGene KnockoutGFP0
(0)

ALAS-E HDR Plasmid (m)

sc-419074-HDRmHomology Directed RepairPuromycin0
(0)

ALAS-E Double Nickase Plasmid (m)

sc-419074-NICmGene KnockoutPuromycin0
(0)

ALAS-E Double Nickase Plasmid (m2)

sc-419074-NIC-2mGene KnockoutPuromycin0
(0)

ALAS-H CRISPR/Cas9 KO Plasmid (h)

sc-406443hGene KnockoutGFP0
(0)

ALAS-H HDR Plasmid (h)

sc-406443-HDRhHomology Directed RepairPuromycin0
(0)

ALAS-H Double Nickase Plasmid (h)

sc-406443-NIChGene KnockoutPuromycin0
(0)

ALAS-H Double Nickase Plasmid (h2)

sc-406443-NIC-2hGene KnockoutPuromycin0
(0)

ALAS-H Double Nickase Plasmid (m)

sc-419073-NICmGene KnockoutPuromycin0
(0)

ALAS-H Double Nickase Plasmid (m2)

sc-419073-NIC-2mGene KnockoutPuromycin0
(0)

ALAS CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ALAS-E CRISPR Activation Plasmid (h)

sc-403752-ACThGene ActivationPuro, Blast, Hygro0
(0)

ALAS-E CRISPR Activation Plasmid (h2)

sc-403752-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ALAS-E Lentiviral Activation Particles (h)

sc-403752-LAChGene ActivationPuro, Blast, Hygro0
(0)

ALAS-E Lentiviral Activation Particles (h2)

sc-403752-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ALAS-E CRISPR Activation Plasmid (m)

sc-419074-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ALAS-E CRISPR Activation Plasmid (m2)

sc-419074-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ALAS-E Lentiviral Activation Particles (m)

sc-419074-LACmGene ActivationPuro, Blast, Hygro0
(0)

ALAS-E Lentiviral Activation Particles (m2)

sc-419074-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ALAS-H CRISPR Activation Plasmid (h)

sc-406443-ACThGene ActivationPuro, Blast, Hygro0
(0)

ALAS-H CRISPR Activation Plasmid (h2)

sc-406443-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ALAS-H Lentiviral Activation Particles (h)

sc-406443-LAChGene ActivationPuro, Blast, Hygro0
(0)

ALAS-H Lentiviral Activation Particles (h2)

sc-406443-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ALAS-H CRISPR Activation Plasmid (m)

sc-419073-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ALAS-H CRISPR Activation Plasmid (m2)

sc-419073-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ALAS-H Lentiviral Activation Particles (m)

sc-419073-LACmGene ActivationPuro, Blast, Hygro0
(0)

ALAS-H Lentiviral Activation Particles (m2)

sc-419073-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ALAS siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ALAS-E siRNA (h)

sc-44726hGene SilencingN/A0
(0)

ALAS-E shRNA Plasmid (h)

sc-44726-SHhGene SilencingPuromycin0
(0)

ALAS-E shRNA (h) Lentiviral Particles

sc-44726-VhGene SilencingPuromycin0
(0)

ALAS-E siRNA (m)

sc-44727mGene SilencingN/A0
(0)

ALAS-E shRNA Plasmid (m)

sc-44727-SHmGene SilencingPuromycin0
(0)

ALAS-E shRNA (m) Lentiviral Particles

sc-44727-VmGene SilencingPuromycin0
(0)

ALAS-H siRNA (h)

sc-44728hGene SilencingN/A0
(0)

ALAS-H shRNA Plasmid (h)

sc-44728-SHhGene SilencingPuromycin0
(0)

ALAS-H shRNA (h) Lentiviral Particles

sc-44728-VhGene SilencingPuromycin0
(0)

ALAS-H siRNA (m)

sc-44729mGene SilencingN/A0
(0)

ALAS-H shRNA Plasmid (m)

sc-44729-SHmGene SilencingPuromycin0
(0)

ALAS-H shRNA (m) Lentiviral Particles

sc-44729-VmGene SilencingPuromycin0
(0)