ALAS-H Antibody (C-6): sc-137094
- ALAS-H Antibody (C-6) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 57-210 mapping near the N-terminus of ALAS-H of mouse origin
- recommended for detection of precursor and mature ALAS-H of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for ALAS-H Antibody (C-6) for WB and IHC(P) applications. These reagents are now offered in bundles with ALAS-H Antibody (C-6) (see ordering information below).
ALAS-H Antibody (C-6) is a mouse monoclonal IgG2a antibody that detects 5-aminolevulinate synthase 1 (ALAS-H) in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ALAS-H plays a crucial role in the heme biosynthetic pathway, specifically mediating the synthesis of early heme in the mitochondria of most cells, which is essential for the production of hemoglobin and other heme-containing proteins. Proper functioning of ALAS-H is vital for maintaining cellular respiration and energy production, as heme is a key component of cytochromes involved in the electron transport chain. Additionally, ALAS-H′s housekeeping function ensures that heme synthesis is adequately regulated across various tissues, which is particularly important in conditions where heme demand fluctuates, such as during erythropoiesis or in response to oxidative stress. Anti-ALAS-H antibody (C-6) allows researchers to investigate ALAS-H expression and regulation in different biological contexts, providing insights into disorders related to heme metabolism and potential therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ALAS-H Antibody (C-6) | sc-137094 | 200 µg/ml | $316.00 | |||
ALAS-H Antibody (C-6): m-IgG Fc BP-HRP Bundle | sc-539933 | 200 µg Ab; 10 µg BP | $354.00 | |||
ALAS-H Antibody (C-6): m-IgG2a BP-HRP Bundle | sc-546821 | 200 µg Ab; 10 µg BP | $354.00 |