AKAP 79 Activators
AKAP 79 activators comprise a range of chemicals that can indirectly influence the activity of AKAP 79, a scaffold protein known for its role in coordinating the assembly of enzyme complexes, particularly those involving PKA (Protein Kinase A). These activators do not directly bind or activate AKAP 79; instead, they modulate the cellular signaling pathways that influence the activity of enzymes associated with AKAP 79, especially through the regulation of cAMP levels.
The primary mechanism through which these compounds influence AKAP 79 is by modulating cAMP levels within cells. Compounds like Forskolin, Caffeine, Rolipram, Epinephrine, Isoproterenol, IBMX, Dopamine, Histamine, Prostaglandin E2, Glucagon, Adenosine, and Nicotine interact with various components of cellular signaling pathways, such as G-protein-coupled receptors, adenylate cyclase, and phosphodiesterases.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels. Elevated cAMP can modulate PKA activity, which associates with AKAP 79, potentially influencing its scaffold function. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine inhibits phosphodiesterases, leading to increased cAMP levels. This can indirectly affect AKAP 79 by altering the activity of PKA and other enzymes associated with it. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram, a phosphodiesterase inhibitor, increases cAMP levels, potentially influencing AKAP 79 activity by modulating associated PKA activity. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine, through G-protein-coupled receptor signaling, can increase cAMP levels, indirectly affecting AKAP 79 by altering PKA activity. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol, a beta-adrenergic agonist, can increase cAMP levels, potentially influencing AKAP 79 activity through modulation of PKA. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX, a non-specific phosphodiesterase inhibitor, increases cAMP levels, which can indirectly influence AKAP 79 by modulating associated PKA activity. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine can increase cAMP levels through its action on dopamine receptors, indirectly affecting AKAP 79 activity by modulating PKA. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine, acting on GPCRs, can influence cAMP levels, potentially affecting AKAP 79 activity indirectly. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2 activates GPCRs, leading to changes in cAMP levels, potentially influencing AKAP 79 activity indirectly. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Adenosine, acting through its GPCRs, can modulate cAMP levels, potentially influencing AKAP 79 activity by affecting associated PKA activity. | ||||||