AIRE-1 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor known to alter chromatin structure and affect gene expression. Its inhibition of histone deacetylase activity can lead to changes in the expression of various genes, potentially including AIRE-1. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a cytidine analog that incorporates into DNA and RNA, resulting in hypomethylation of DNA. Changes in DNA methylation patterns can influence gene expression, potentially affecting AIRE-1 levels. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Suberoylanilide Hydroxamic Acid, another histone deacetylase inhibitor, modifies chromatin structure to influence gene expression. It could potentially impact the expression of AIRE-1 through alterations in chromatin accessibility. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, a short-chain fatty acid, has been shown to inhibit histone deacetylase activity, potentially modifying gene expression. It may impact AIRE-1 expression through changes in chromatin structure. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Disulfiram, primarily used for alcohol dependence, can inhibit aldehyde dehydrogenase, but it also has effects on various signaling pathways. It may indirectly affect AIRE-1 expression through these pathways. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib is a proteasome inhibitor that affects protein degradation. By influencing protein turnover, it could potentially impact the stability and expression levels of AIRE-1. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 is another proteasome inhibitor that can influence protein degradation and turnover, potentially affecting AIRE-1 expression levels. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid, often studied in the research of epilepsy, inhibits histone deacetylase. This may result in alterations in gene expression and could potentially affect AIRE-1 expression. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $214.00 $622.00 | 1 | |
Romidepsin is a histone deacetylase inhibitor used in cancer therapy. It can alter gene expression by changing chromatin structure, potentially impacting AIRE-1 levels. | ||||||
Apicidin | 183506-66-3 | sc-202061 sc-202061A | 1 mg 5 mg | $108.00 $336.00 | 9 | |
Apicidin is a potent histone deacetylase inhibitor that can lead to changes in chromatin structure and gene expression. Its impact on histone acetylation levels could potentially affect AIRE-1 expression. | ||||||