AHDC1 Activators
AHDC1 activators encompass a range of compounds that can influence the transcriptional landscape in which AHDC1 operates. Agents like 5-Aza-2'-deoxycytidine and Trichostatin A work to alter DNA methylation and histone acetylation respectively, which are key epigenetic mechanisms affecting gene expression. Changes in these epigenetic marks can lead to the upregulation of genes that encode transcriptional regulators or core components of the transcription machinery, enhancing AHDC1 transcriptional activity. These chemicals do not act directly on AHDC1 but modify the cellular environment in a manner that can lead to increased AHDC1 function.
Furthermore, small molecules like Retinoic acid and Beta-estradiol exert their effects by binding to nuclear receptors that influence gene expression. These nuclear receptors might interact with genomic regions that are near or associated with AHDC1, modulating its activity. Similarly, Forskolin and PMA, through the elevation of cAMP and activation of PKC respectively, can lead to the phosphorylation of various proteins including transcription factors. This post-translational modification may alter the interaction between these factors and AHDC1, affecting its activity indirectly.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A molecule that influences gene expression by activating nuclear receptors. These receptors can bind to DNA at sites that may be in proximity to or involved with AHDC1-associated genes, potentially increasing AHDC1 activity by association. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Elevates cAMP levels and activates PKA, which may lead to phosphorylation of transcription factors and cofactors interacting with AHDC1, thus modulating its activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol that can modulate various signaling pathways, possibly influencing transcription factors and cofactors that interact with or regulate AHDC1. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
As a hormone, it can modulate gene expression by activating estrogen receptors which might interact with regulatory regions of genes related to AHDC1 activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activator of protein kinase C (PKC) which may affect downstream signaling pathways influencing transcription factor activity, including those associated with AHDC1. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A histone deacetylase inhibitor which can lead to chromatin remodeling, potentially affecting the transcription of genes regulated by AHDC1 or those regulating AHDC1 itself. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Modulates the Wnt signaling pathway and could influence the transcriptional machinery interacting with AHDC1 by altering the expression of genes controlled by Wnt signaling. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $184.00 $668.00 | 2 | |
Donor of methyl groups used in DNA methylation; could affect the methylation status of genes related to AHDC1, thus impacting its activity indirectly. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $31.00 $117.00 $918.00 | 136 | |
Solvent often used to dissolve other chemicals; can influence various cellular processes and might affect transcription factor binding or activity, thereby potentially influencing AHDC1. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc ion is important for the function of many DNA-binding proteins and could influence the activity of transcription factors and associated proteins that regulate or interact with AHDC1. | ||||||