ADHβ Activators
ADHβ activators belong to a class of chemical compounds designed to modulate the activity of ADHβ, which stands for Alcohol Dehydrogenase β-subunit. Alcohol dehydrogenases are a family of enzymes that play a crucial role in the metabolism of alcohol and other alcohols in the body. These enzymes are responsible for catalyzing the conversion of alcohols into their corresponding aldehydes or ketones by facilitating the transfer of hydrogen atoms from the alcohol to coenzymes like nicotinamide adenine dinucleotide (NAD) or nicotinamide adenine dinucleotide phosphate (NADP). ADHβ is a specific subunit of alcohol dehydrogenase enzymes, and its activity contributes to the breakdown and detoxification of ethanol, the primary alcohol found in alcoholic beverages.
ADHβ activators are designed to interact with ADHβ and potentially enhance its enzymatic activity. By targeting ADHβ, these compounds may influence the efficiency of alcohol metabolism, affecting the rate at which ethanol is converted into acetaldehyde during the process of alcohol detoxification. Research on ADHβ activators provides insights into the molecular mechanisms that govern alcohol metabolism and the role of ADHβ in this process. Understanding the molecular interactions between ADHβ and its activators is crucial for deciphering the complex biochemical pathways involved in alcohol metabolism and its implications for alcohol tolerance and susceptibility to alcohol-related health issues. Further investigation is needed to elucidate the precise mechanisms of action and potential biological consequences associated with ADHβ activation, contributing to our knowledge of alcohol metabolism and its impact on human physiology.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
As a product of retinol metabolism by ADH, retinoic acid may feedback regulate the expression of ADHβ to control retinoid levels. | ||||||
2-Propanol | 67-63-0 | sc-391000C sc-391000 sc-391000B sc-391000A | 1 ml 25 ml 100 ml 500 ml | $32.00 $52.00 $62.00 $87.00 | 1 | |
Isopropanol is another substrate for ADH enzymes and could potentially increase ADHβ expression upon exposure. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $38.00 $60.00 $143.00 $306.00 $1012.00 | 5 | |
Found in cruciferous vegetables, it can modulate liver enzymes, potentially affecting ADHβ expression. | ||||||
D-(−)-Fructose | 57-48-7 | sc-221456 sc-221456A sc-221456B | 100 g 500 g 5 kg | $40.00 $89.00 $163.00 | 3 | |
High fructose consumption can alter liver metabolism and might influence the expression of ADHβ. | ||||||
Benzene | 71-43-2 | sc-239290 | 1 L | $77.00 | ||
As a toxin, benzene metabolism involves liver enzymes, and chronic exposure could modulate ADHβ expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Present in broccoli, it can affect phase I and phase II liver enzymes, potentially influencing ADHβ expression. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
As a form of vitamin B3, nicotinamide can modulate metabolic processes and may have a regulatory effect on ADHβ expression. | ||||||