Date published: 2025-12-7

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Adenomatous Polyposis coli Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Adenomatous Polyposis coli monoclonal antibodies for research in cellular processes. Adenomatous Polyposis coli Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Adenomatous Polyposis coli protein functions as a tumor suppressor involved in regulating cell growth and adhesion, with significant involvement in the Wnt signaling pathway. Mutations in the APC gene frequently occur in familial adenomatous polyposis and colorectal cancer, making it a crucial area of focus in cancer research. Research on Adenomatous Polyposis coli protein regulation and function continues to reveal new insights into tumorigenesis. Understanding the mechanisms of APC gene mutations helps identify potential therapeutic approaches for cancer treatment. Investigating Adenomatous Polyposis coli protein interactions advances knowledge of cellular signaling networks and disease progression. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to make meaningful discoveries in cancer biology and therapeutic development.

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Adenomatous Polyposis coli Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

APC Antibody (F-3)

sc-9998mouse IgG1 κ2-289 (h)WB, IP, IF, IHC(P), ELISAm, r, h
32
(20)

APC Antibody (ALi 12-28)

sc-53165mouse IgG1 κ1-433 (h)WB, IP, IFh
13
(6)

APC Antibody (A-3)

sc-393704mouse IgG2b κ2-19 (h)WB, IP, IF, ELISAm, r, h
4
(3)

APC Antibody (c-APC 28.9)

sc-53166mouse IgG1 κC-Terminal (h)WB, IP, IF, IHC(P)m, r, h

new

(5)

Adenomatous Polyposis coli CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

APC CRISPR/Cas9 KO Plasmid (h)

sc-400374hGene KnockoutGFP
1
(0)

APC HDR Plasmid (h)

sc-400374-HDRhHomology Directed RepairPuromycin
1
(0)

APC Double Nickase Plasmid (h)

sc-400374-NIChGene KnockoutPuromycin
1
(0)

APC Double Nickase Plasmid (h2)

sc-400374-NIC-2hGene KnockoutPuromycin
1
(0)

APC CRISPR/Cas9 KO Plasmid (m)

sc-419146mGene KnockoutGFP0
(0)

APC HDR Plasmid (m)

sc-419146-HDRmHomology Directed RepairPuromycin0
(0)

APC Double Nickase Plasmid (m)

sc-419146-NICmGene KnockoutPuromycin0
(0)

APC Double Nickase Plasmid (m2)

sc-419146-NIC-2mGene KnockoutPuromycin0
(0)

Adenomatous Polyposis coli CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

APC CRISPR Activation Plasmid (h)

sc-400374-ACThGene ActivationPuro, Blast, Hygro
1
(0)

APC CRISPR Activation Plasmid (h2)

sc-400374-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

APC Lentiviral Activation Particles (h)

sc-400374-LAChGene ActivationPuro, Blast, Hygro
1
(0)

APC Lentiviral Activation Particles (h2)

sc-400374-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

APC CRISPR Activation Plasmid (m)

sc-419146-ACTmGene ActivationPuro, Blast, Hygro0
(0)

APC CRISPR Activation Plasmid (m2)

sc-419146-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

APC Lentiviral Activation Particles (m)

sc-419146-LACmGene ActivationPuro, Blast, Hygro0
(0)

APC Lentiviral Activation Particles (m2)

sc-419146-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Adenomatous Polyposis coli siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

APC siRNA (h)

sc-29702hGene SilencingN/A
3
(1)

APC shRNA Plasmid (h)

sc-29702-SHhGene SilencingPuromycin
3
(1)

APC shRNA (h) Lentiviral Particles

sc-29702-VhGene SilencingPuromycin
3
(1)

APC siRNA (m)

sc-29703mGene SilencingN/A
3
(0)

APC shRNA Plasmid (m)

sc-29703-SHmGene SilencingPuromycin
3
(0)

APC shRNA (m) Lentiviral Particles

sc-29703-VmGene SilencingPuromycin
3
(0)